… based on mutual information is a powerful method for the prediction of drug resistance and
susceptibility from complex mutational patterns for a broad spectrum of antiretroviral drugs. …

… drug resistance. Specifically, we will review the mounting evidence that the genetic diversity
within MTBC, albeit limited (2), lies at the heart of both intrinsic and acquired drug resistance…

… of resistance. We examine and compare mechanisms of drug resistance in these diverse
biological … is only possible to the extent that it does not break the complex cycle of transmission. …

… on drug resistance. We … diversity in the Mycobacterium tuberculosis complex (MTBC),
the causative agent of human TB, and how this diversity influences the emergence of drug-resistant …

… the cardinal features of drug resistance into specific biological mechanisms … of drug resistance;
see 8). As demonstrated below, the specific biological mechanisms are at least as diverse …

… , drug-sensitive cell. The population grows unrestricted and accumulates drug-resistant cells
… to the genetic diversity of drug-resistant mutations in the drug-resistant subpopulation. To …

… regarding the epidemiology and resistance patterns to anti-TB drugs in children [6]. The aim
of this study was to determine the genotype diversity and the extent of drug resistance in M. …

… of drug resistance and therapy failure. While gene mutations pre-existing in the tumor or
acquired during therapy can drive drug resistance, cancers can also evade drug … the diverse and …

… The “pure” subtype I was evidenced as being a complex recombinant involving subtypes A,
… on HIV drug design, acquisition of drug resistance mutations, genotyping for drug resistance …

… the complexity of RR-TB strains circulating in Hunan province with complex additional
drug-resistant … Therefore, this study aims to better understand the genetic diversity, drug-resistant …