Origins and diversity of macrophages in health and disease

G Sreejit, AJ Fleetwood, AJ Murphy… - Clinical & …, 2020 - Wiley Online Library
… the importance of ontogeny in macrophage dysfunction in disease. In this review, we …
macrophages, the mechanisms of macrophage specialisation and their role in health and disease. …

Functional diversity of macrophages in vascular biology and disease

I Park, C Kassiteridi, C Monaco - Vascular Pharmacology, 2017 - Elsevier
… In this review we will explore the current concept of macrophage biology, together with
the functional diversity of macrophage populations in vascular biology by weaving the recent …

[HTML][HTML] Macrophages in health and disease

MD Park, A Silvin, F Ginhoux, M Merad - Cell, 2022 - cell.com
… of different macrophages. We propose that the ontogeny of a macrophage—beyond its …
differentiation, amidst steady-state cues, disease-associated signals, and time—constitutes …

Macrophages at the fork in the road to health or disease

CD Mills, LL Lenz, K Ley - Frontiers in immunology, 2015 - frontiersin.org
… Burrack and Morrison discusses how macrophage activation and arginine metabolism by
M1- or M2-type macrophages can have diverse effects on health and disease during viral …

Brain macrophage development, diversity and dysregulation in health and disease

A Silvin, J Qian, F Ginhoux - Cellular & molecular immunology, 2023 - nature.com
… functional programs during brain development, homeostasis and disease pathogenesis. …
macrophages during development and healthy aging. We then discuss how brain macrophages

Diversity of intestinal macrophages in inflammatory bowel diseases

AA Kühl, U Erben, LI Kredel, B Siegmund - Frontiers in immunology, 2015 - frontiersin.org
… Chronic inflammation in inflammatory bowel diseases massively alters the … diversity of
intestinal macrophages. We here address the diversity within the human intestinal macrophage

Macrophage polarization in health and disease

L Cassetta, E Cassol, G Poli - The Scientific World Journal, 2011 - Wiley Online Library
… There is a high number of factors contributing to diversity of macrophage function, including
the synergistic or antagonistic effects of different cytokines and related signals on their …

Occurrences and Functions of Ly6Chi and Ly6Clo Macrophages in Health and Disease

Y Li, Y Zhang, G Pan, L Xiang, D Luo… - Frontiers in …, 2022 - frontiersin.org
… and Ly6C lo macrophages, including their origin, differentiation, and phenotypic switching,
and the diverse functions of Ly6C hi and Ly6C lo macrophages in homeostasis and disease, …

Macrophage polarization and plasticity in health and disease

SK Biswas, M Chittezhath, IN Shalova, JY Lim - Immunologic research, 2012 - Springer
… versatility of macrophages is evident from their role in diverse … list of diseases where a
deregulated macrophage response … role of macrophages in health and disease, discussing their …

Diversity, mechanisms, and significance of macrophage plasticity

M Locati, G Curtale, A Mantovani - … : Mechanisms of Disease, 2020 - annualreviews.org
health and disease has added a new dimension to our understanding of the diversity of
macrophage … networks underlie the adaptability of macrophages to different environmental cues. …