… We hypothesized that oxidative stress-induced DNA damage could be a contributor for PCB
… exposure and oxidative DNA adduct formation. Female Sprague–Dawley rats were exposed …

… rats; however, the identity of these adducts is unknown. In the present study, we have
characterized the DNA adducts … of hepatic DNA adduct formation in rats administered toremifene, …

… DNA alkylation seems to be responsible for the triggering of apoptosis. In this study, after male
adult Sprague–Dawley rats … -G) as the biomarkers for DNA damage were measured in the …

… in the target organ of cancer (liver) and nontarget organ of cancer (kidney) of Sprague
Dawley rats exposed to DES. We have selected Male Sprague Dawley rats as an experimental …

… Male Sprague Dawley rats, weighing 275–325 g, were obtained from the Centre d’Elevage
Janvier (Laval, France). They were housed in plastic cages, in an air-conditioned room …

… analyzed the DNA adducts present in the target tissues. Using the n-butanol adductenhancement
modification (20) of the P-postlabeling assay (21), we have detected DNA adducts in …

… This paper is an evaluation of the DNA adduct formation of DMBA and its noncarcinogenic
… (target organ) DNA of female Sprague-Dawley rats. This study expands (via adduct analysis) …

… Male and female Sprague-Dawley rats were treated by gas tric intubation either 1, 2, 3, or 4
… The major DNA adduct formed in rat liver in vivo is a nonacetylated product which probably …

… occurring in early stage of toxicity in rats exposed to 1-BP, the … 1-BP on adduct formation with
DNA and GSH in male rats. In … of DNA adducts were found in livers of 1-BP treated male SD …

… on total DMBA-DNA binding (measured by total tritium bound to DNA) in the liver and mammary
tissues of female SpragueDawley rats in vivo.At the age of 6 wk. rats in the experimental …