… Reactions of the sulphonium ion of sulphur mustard (SM +1 ) at the N7, … DNA bases and
shows that SM +1 would form stable adducts at the endocyclic nitrogen sites of the DNA bases, …

… (HR) DNA repair pathway promotes cell survival after SM. This study investigated the role
of other DNA repair pathways in the cellular response to SM, specifically base excision repair (…

… Sulphur mustard (HD) is a blister agent for which no specific … This study examined DNA
damage in thymocytes exposed to a … The sulphur mustard used in this study was synthesised and …

… of alkylation by sulphur mustard of a DNA fragment containing … We demonstrate that sulphur
mustard alkylation of the DNA … appear to involve an intervening base pair between the two …

… The differences may be explained in part by the differences in base composition between …
interactions to reactions involving the nitrogen mustard aziridinium cation. SM reacts with …

… Sulphur mustard (SM) is a chemical warfare agent that attacks … DNA represents one of the
most critical molecular targets of … are expressed as the number of adduct per million bases. …

… Quantitative release of DNA lesions is a requisite to any type of chromatographic detection
of DNA base damage. As previously emphasized (Boysen et al. Citation2009), this has been …

… Bis(2-chlomthyl) sulphi& commonly known as sulphur mustard (SM) is highly reactive … the
principal target organs and the &oxyribose nucleic acid (DNA) is the most important molecular …

… Using both model human lymphoblastoid cell lines and pharmacological inhibitors, it was
found that DNA damage induced by CEES was repaired by base excision repair (BER) and …

… mustard (SM) is a chemical warfare agent which is cytotoxic in nature, and at the molecular
level, SM acts as DNA … by changing the pattern of nucleotides bases or through breaking the …