Mitochondrial DNA content affects the fertilizability of human oocytes

P Reynier, P May-Panloup, MF Chretien… - Molecular human …, 2001 - academic.oup.com
… that mitochondrial DNA content could play a role in oocyte fertilizability. A significant reduction
in mtDNA content was observed in oocytes from group 2 in comparison with oocytes from …

DNA damage and repair in human oocytes and embryos: a review

Y Ménézo, B Dale, M Cohen - Zygote, 2010 - cambridge.org
… In this review we focus on the expression of mRNAs that regulate DNA repair capacity in
the human oocyte and the mechanisms that protect the embryo against de novo damage. …

Fertilization and embryology: The early development and DNA content of activated human oocytes and parthenogenetic human embryos

AS Taylor, PR Braude - Human reproduction, 1994 - academic.oup.com
DNA content using a computerized image analysis system showed that activated oocytes with
one pronudeus had a DNA contentoocytes to replicate their DNA was also demonstrated. …

Mitochondrial DNA rearrangements in human oocytes and embryos

JA Barritt, CA Brenner, J Cohen… - Molecular Human …, 1999 - academic.oup.com
… of human oocytes or embryos that contained mtDNA rearrangements. Significant reductions
in the number of oocytes … to determine the ATP content of human oocytes in association with …

Low oocyte mitochondrial DNA content in ovarian insufficiency

P May-Panloup, MF Chretien, C Jacques… - Human …, 2005 - academic.oup.com
DNA (mtDNA) in 116 oocytes obtained from 47 women undergoing the ICSI procedure. We
compared the mtDNA content of oocytes … ) ATP content of human oocytes and developmental …

Mitochondrial DNA content and 4977 bp deletion in unfertilized oocytes

CCW Chan, VWS Liu, EYL Lau… - Molecular human …, 2005 - academic.oup.com
… in unfertilized oocytes in relation to donors’ age have been controversial… oocytes and relate
them to the donors’ age. Fifty-two women donated 155 unfertilized metaphase II (MII) oocytes

Assessment of the cellular DNA content of whole mounted mouse and human oocytes and of blastomeres containing single or multiple nuclei

NJ Winston, MH Johnson, PR Braude - Zygote, 1993 - cambridge.org
… the case with human oocytes and embryos. … DNA content in both live and fixed mouse
oocytes and blastomeres, (including multinucleated cells) and on whole-mounted human oocytes

[HTML][HTML] The association of reproductive senescence with mitochondrial quantity, function, and DNA integrity in human oocytes at different stages of maturation

HE Duran, F Simsek-Duran, SC Oehninger… - Fertility and sterility, 2011 - Elsevier
content of oocytes increases in parallel with maturational stage. It is generally believed that
human oocytes … the increase in ATP content by advancing oocyte maturational stage that we …

Mitochondrial DNA deletion in human oocytes and embryos.

CA Brenner, YM Wolny, JA Barritt… - Molecular human …, 1998 - academic.oup.com
DNA (mtDNA) deletions are present in both human oocytes … deletion was investigated in
human oocytes and embryos. … of the KSS deletion in 74 human oocytes and 137 embryos was …

Expression profiling of DNA repair genes in human oocytes and blastocysts using microarrays

S Jaroudi, G Kakourou, S Cawood, A Doshi… - Human …, 2009 - academic.oup.com
… Subsequent to this, DNA repair is expected to have a major impact on embryo development.
human oocytes express DNA repair genes at high levels allowing low tolerance for DNA