… of DNA repair where histone modifications act as signals and landing platforms for various
repair proteins. … of histone modifications and their role in the maintenance of genome integrity. …

… and other components of damaged chromatin also become modified by acetylation and …
combinations of histone modifications affect the accumulation and function of DNA repair factors (…

… covalent histone modifications have been implicated in the response to double-stranded
DNA … identify the DSB, activate the DNA damage checkpoint, and repair the break. Chromatin …

… the importance of H3K4me3 in DNA damage repair processes, we asked whether or not
this histone modification could be induced at the site of DNA damage. First, we tested whether …

… modifications and their importance in plant DNA repair is … for amino acids) of the histone
variant H2AX by the DSB signalling … and highly conserved response to induction of DNA DSBs, …

… Many histone PTMs are dynamically regulated by DNA damage. For example, one of the
first histone modifications identified in the DDR was the phosphorylation of the …

… step of eukaryotic DSB DNA damage response. Clin Cancer … ), other histone modifications
induced by DNA damage have … an effect of DNA damage–induced histone modifications on …

… Thus histone modifications can influence DNA damage responses during signaling as well
as during the opening and restoration of chromatin to its original native state. In addition to …

… major histone modifications and their functions in orchestrating the response to DNA DSBs.
… important interactions between different histone modifications in DNA damage responses. …

… play well-recognized roles in sensing, processing, and repairing damaged DNA to ensure …
understanding of histone modifications as they relate to DNA damage responses (DDRs) and …