… DNA damage is determined by the primary DNA sequence, with chromatin structure having
a limited effect. The data suggest a model in which DNA-… of target gene DNA relative to non-…

… , inability to increase dNTP levels after DNA damage exposure leads to higher frequencies
… cannot maintain dNTP levels exhibit higher frequencies of spontaneous and DNA damage-…

… via base excision and nucleotide excision pathways. The levels of oxidative DNA damage
reported in many human tissues or in animal models of carcinogenesis exceed the levels of …

… DNA damage by the human nucleotide excision repair (NER) pathway. NER is an evolutionarily
conserved DNA … recognition process in GGR is regulated at multiple levels, through …

… with the induction of DNA damage repair genes. Under limited … induction of DNA damage
response, pyrimidine nucleotide … found that the deoxyribose nucleotide salvage pathway has …

… In our study, the level of endogenous DNA damage was significantly affected by gender. A
… The level of endogenous DNA damage found in our study population is in agreement with …

… –DNA adducts, and their repair, to be studied at various levels of resolution from gene regions
to the individual nucleotide level in … measures the total damage on both DNA strands in a …

… nucleotide pool and protects cells from DNA damage, we hypothesized that high-SIRT5 levels
… Our results indicated that SIRT5 knockdown reduced R5P and nucleotide levels in CRC …

… Elevated oxidative stress and DNA damage and repair levels in urinary bladder carcinomas
… Elevated oxidative stress and DNA damage and repair levels in urinary bladder carcinomas …

… events in the DNA repair process, suggesting that p53 has additional effects much earlier
after DNA damage. One clue was the consistent observation that the basal levels of DDB2 and …