… induced the greatest extent of DNA damage in target organs for carcinogenicity. … carcinogen,
caused exten sive DNA damage in all tissues evaluated. To date, the in vitro DNA damage-…

… In addition to its effects on DNA damage, folate deficiency impacts on DNA repair by …
The effects of folate status on DNA methylation and potentially on colon carcinogenesis are …

… This review focuses on the role of oxidatively induced DNA lesions in colon carcinogenesis.
… generation of DNA damage and mutations) and multiple molecular steps in the colon cancer …

… DNA synthesis in the proliferative zone of the crypts. An acute 4-hour in vitro exposure to 0.5
mM of the colon-selective carcinogens 1,… and persistent effects of colon carcinogens can be …

… The present study was designed to investigate whether propolis exerts a protective effect
on colon carcinogenesis and on DNA damage in Wistar rats by using the aberrant crypt foci …

… In rat colon cells, we have found distinct DNA damaging activity by PhIP indicating that, in
this … In human colon cells, however, PhIP did not induce DNA damage. These results are in …

… in rats treated with the colon carcinogen 1,2-dimethylhydrazine (DMH). In addition, DNA
damage in colon … to determine the effect of annatto on DMH-induced rat colon carcinogenesis. …

… DNA damage, DNA repair, the expression levels and activities of … in colon tissues of all
groups. Our results showed significant suppression of DNA damage and induction of DNA repair …

… The aim of the present study was to investigate the ability of RA to prevent chemically induced
primary DNA damage and preneoplastic lesions in rat colon using the comet and aberrant …

… glycosylase (Aag) to initiate base excision repair. Using a mouse … DNA repair prevents
colonic epithelial damage and reduces the severity of dextran sulfate sodium–induced colon …