DNA methylation and demethylation in mammals

Z Chen, AD Riggs - Journal of Biological Chemistry, 2011 - ASBMB
… , a wave of global de novo methylation re-establishes the DNA methylation patterns that will
be maintained, in large part, in somatic tissues. Genome-wide demethylation also occurs in …

Mechanisms of DNA methylation and demethylation in mammals

G Auclair, M Weber - Biochimie, 2012 - Elsevier
… of DNA methylation are highly dynamic between cell types. Here, we discuss the importance
of DNA methylation for genome regulation and the mechanisms that remodel the DNA

DNA methylation and its basic function

LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
DNA methylation and demethylation. As a consequence, differentiated cells develop a stable
and unique DNA methylation … the process of DNA methylation and demethylation in the …

DNA demethylation

AP Wolffe, PL Jones, PA Wade - Proceedings of the …, 1999 - National Acad Sciences
… Understanding the biochemistry of DNA methylation dynamics is a problem of tremendous …
molecular mechanisms that target both DNA methylation and demethylation is essential. Such …

DNA methylation and demethylation: a pathway to gametogenesis and development

W Dean - Molecular Reproduction and Development, 2014 - Wiley Online Library
… addition and subtraction of DNA methylation and its oxidative products, coupled to the
mechanisms at play to achieve this goal. The activities competent to add DNA methylation, and …

DNA methylation and demethylation as targets for anticancer therapy

M Szyf - Biochemistry (Moscow), 2005 - Springer
… of DNA methylation were shown to activate methylated tumor suppressor genes and inhibit
tumor growth, demethylation of … This review discusses the emerging role of demethylation in …

DNA methylation and demethylation in plant immunity

A Deleris, T Halter, L Navarro - Annual review of phytopathology, 2016 - annualreviews.org
… Here, we focus on DNA methylation, which refers to the … biological relevance of DNA
methylation, as well as demethylation, in … Furthermore, we present the dynamics of DNA

Target specificity of mammalian DNA methylation and demethylation machinery

M Ravichandran, RZ Jurkowska… - Organic & biomolecular …, 2018 - pubs.rsc.org
… maintenance of the methylation pattern, both generation of DNA methylation and its removal
… of ongoing DNA methylation and demethylation shapes the final epigenetic methylation

Methylation and demethylation in the regulation of genes, cells, and responses in the immune system

DR Fitzpatrick, CB Wilson - Clinical immunology, 2003 - Elsevier
DNA methylation is a focus of epigenetic research in the immune system. This overview
begins with a synopsis of the players and processes involved in DNA methylation, demethylation

DNA methylation and demethylation probed by small molecules

M Szyf - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2010 - Elsevier
… of the DNA demethylating activity is still a mystery, the development of DNA demethylation
inhibitors … This review will discuss DNA methylation and demethylation machineries, and their …