DNA methylation pathways and their crosstalk with histone methylation

J Du, LM Johnson, SE Jacobsen… - Nature reviews Molecular …, 2015 - nature.com
DNA methylation is established by specialized de novo DNA methyltransferase enzymes and
is present in three different DNAmethylated in cells reduced in a H3K4 demethylase 119 . …

The role of DNA (de) methylation in immune responsiveness of Arabidopsis

A López Sánchez, JHM Stassen, L Furci… - The Plant …, 2016 - Wiley Online Library
… Our study has shown that DNA methylation and demethylation activities antagonistically
regulate basal resistance of Arabidopsis. While previous studies reported similar effects by …

DNA methylation analysis: a review of current methodologies

EJ Oakeley - Pharmacology & therapeutics, 1999 - Elsevier
… The relationship between levels of DNA methylation and gene activity has been known for
… the other allows the demethylation of DNA in nondividing cells (the Bhattacharya enzyme). …

Dynamic reprogramming of DNA methylation in the early mouse embryo

F Santos, B Hendrich, W Reik, W Dean - Developmental biology, 2002 - Elsevier
… In contrast to previous work, we show that demethylation of the male pronucleus is …
pronuclei underwent demethylation in the same oocyte. Paternal demethylation in fertilised …

A practical guide to the measurement and analysis of DNA methylation

BD Singer - American journal of respiratory cell and molecular …, 2019 - atsjournals.org
DNA demethylation can occur passively during DNA replication or via the catalytic activity of
… of its thermodynamic stability, DNA methylation and demethylation are in fact quite dynamic, …

DNA methylation dynamics in cellular commitment and differentiation

M Suelves, E Carrió, Y Núñez-Álvarez… - Briefings in functional …, 2016 - academic.oup.com
… , DNA methylation has been … DNA methylation in different genomic contexts, revealing a
more dynamic regulation than originally thought, as active DNA methylation and demethylation

Chemical and biochemical approaches in the study of histone methylation and demethylation

KK Li, C Luo, D Wang, H Jiang… - Medicinal research …, 2012 - Wiley Online Library
… As early as 1983, Feinberg et al. observed a global reduction of DNA methylation content in
… A number of tumor-specific genes are found to be regulated by DNA methylation and histone …

Mechanisms of DNA Methylation and Demethylation During Mammalian Development

Z Ying, T Chen - Handbook of Epigenetics, 2023 - Elsevier
… These include DNA methyltransferases, which catalyze the transfer of a methyl … demethylation.
In this chapter, we will discuss the mechanisms of DNA methylation and demethylation in …

DNA methylation of cancer genome

HH Cheung, TL Lee, OM Rennert… - Birth Defects Research …, 2009 - Wiley Online Library
DNA methylation plays an important role in regulating normal development and carcinogenesis.
Current understanding of the biological roles of DNA methylation is limited to its role in …

Active DNA demethylation mediated by DNA glycosylases

JK Zhu - Annual review of genetics, 2009 - annualreviews.org
… This review also discusses other possible mechanisms of active DNA demethylation,
how genome DNA methylation status might be sensed to regulate the expression of …