… "We now come to realize that DNA methylation is not static," says He. Rather, much of the
genome exists as "a dynamic equilibrium of methylation and demethylation." DNA methylation …

… methyltransferase activity, but in this setting inhibited activity has not been conclusively
shown to affect DNA methylation per se. Any clinical effect of these weak “demethylating” drugs …

… Several lines of evidence strongly suggest that DNA methylation is involved in embryo …
active demethylation starting promptly after fertilization. Except for a small number of methylated …

… In this Review we provide a map of the DNA methylation landscape, … We also discuss how
DNA methylation could provide a … Demethylation is mediated by the TET enzymes that convert …

… of DNA methylation in relation to the presence of DNA strand … to the dynamics of paternal
DNA methylation, monitored by Ab … active DNA demethylation and DNA repair in the zygote. …

… modifications at the DNA level, especially active DNA demethylation, in gene activation are
not well understood 3,4,5 . Here we report that DNA methylation/demethylation is hormonally …

… Note that DNA methylation levels and shaded areas for demethylation processes are
arbitrary, not quantitatively reflecting their contribution to the DNA methylation dynamics. …

… The demethylating agent 5-azacytidine can enhance the efficiency of iPS … DNA demethylase
protein activation-induced cytidine deaminase (AID/AICDA) can erase DNA methylation at …

… In Arabidopsis, much of the DNA methylation is directed by RNA interference (RNAi) …
demethylation and RNAi-mediated DNA methylation. We found that genic regions demethylated by …

… to reverse the transformed phenotype through the use of known or novel demethylating
agents to correct aberrant methylation patterns and restore growth control in tumor cells. …