Repairing DNA-methylation damage
B Sedgwick - Nature reviews Molecular cell biology, 2004 - nature.com
… demethylated by DNA-… the methylated oxygen in DNA to a cysteine residue within the
protein. The 3-methyladenine (3-meA)-DNA-glycosylase and O 6 -methylguanine (O 6 -meG)-DNA-…
protein. The 3-methyladenine (3-meA)-DNA-glycosylase and O 6 -methylguanine (O 6 -meG)-DNA-…
Genetic interactions between DNA demethylation and methylation in Arabidopsis
J Penterman, R Uzawa, RL Fischer - Plant Physiology, 2007 - academic.oup.com
… In Arabidopsis, much of the DNA methylation is directed by RNA interference (RNAi) …
demethylation and RNAi-mediated DNA methylation. We found that genic regions demethylated by …
demethylation and RNAi-mediated DNA methylation. We found that genic regions demethylated by …
DNA methylation in mammalian development and disease
W Dean, D Lucifero, F Santos - Birth Defects Research Part C …, 2005 - Wiley Online Library
… DNA methylation, explore the known enzymatic activities responsible for both establishment
and maintenance of DNA methylation … DNA methylation is defined as passive demethylation. …
and maintenance of DNA methylation … DNA methylation is defined as passive demethylation. …
The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation
J Wang, S Hevi, JK Kurash, H Lei, F Gay, J Bajko… - Nature …, 2009 - nature.com
… Histone methylation and DNA methylation are functionally linked 4,5,6,7,8 . To investigate
whether LSD1 deficiency affects DNA methylation, we measured the 5-methylcytosine content …
whether LSD1 deficiency affects DNA methylation, we measured the 5-methylcytosine content …
Profiling of methylation and demethylation pathways during brain development and ageing
TFJ Kraus, S Kilinc, M Steinmaurer, M Stieglitz… - Journal of Neural …, 2016 - Springer
… The aim of this study was to quantify expression levels of genes that are associated with
DNA methylation/demethylation in different brain regions and at different ages. Therefore, we …
DNA methylation/demethylation in different brain regions and at different ages. Therefore, we …
Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes
… of DNA methylation in relation to the presence of DNA strand … to the dynamics of paternal
DNA methylation, monitored by Ab … active DNA demethylation and DNA repair in the zygote. …
DNA methylation, monitored by Ab … active DNA demethylation and DNA repair in the zygote. …
DNA methylation patterns formation and function
A Razin, M Szyf - Biochimica et Biophysica Acta (BBA)-Gene Structure …, 1984 - Elsevier
… DNA modifications is just starting to become clarified [7, 8]. Besides the well-known function
of DNA methylation … data suggests the association of DNA methylation with gene activity [11-…
of DNA methylation … data suggests the association of DNA methylation with gene activity [11-…
DNA methylation and the regulation of gene transcription
JT Attwood, RL Yung, BC Richardson - Cellular and Molecular Life …, 2002 - Springer
… demethylation, Dnmt1-deficient embryonic stem cells are viable and maintain a low level of
DNA methylation … Furthermore, transfected proviral DNA that becomes integrated undergoes …
DNA methylation … Furthermore, transfected proviral DNA that becomes integrated undergoes …
DNA methylation: past, present and future directions
KD Robertson, P A. Jones - Carcinogenesis, 2000 - academic.oup.com
… to reverse the transformed phenotype through the use of known or novel demethylating
agents to correct aberrant methylation patterns and restore growth control in tumor cells. …
agents to correct aberrant methylation patterns and restore growth control in tumor cells. …
Effect of inflammatory cytokines on DNA methylation and demethylation
J Winfield - 2016 - digitalcommons.pcom.edu
… DNA methylatransferase (DNMT1 and 3a) and demethylase (… Global levels of DNA methylation
following treatment with IL-… of enzymes involved in DNA methylation, resulting in global …
following treatment with IL-… of enzymes involved in DNA methylation, resulting in global …