A DNA methylation atlas of normal human cell types
… In summary, we present a comprehensive methylation atlas of primary human cell types
along with an extensive set of cell-type-specific markers and computation tools for fragment-…
along with an extensive set of cell-type-specific markers and computation tools for fragment-…
DNA methylation atlas of the mouse brain at single-cell resolution
… By combining multi-omic datasets (DNA methylation, chromatin contacts, and open … types
in the mouse brain, our DNA methylation atlas establishes the epigenetic basis for neuronal …
in the mouse brain, our DNA methylation atlas establishes the epigenetic basis for neuronal …
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to
understand mechanisms underpinning gene regulation and disease. In the present study, we …
understand mechanisms underpinning gene regulation and disease. In the present study, we …
Characterizing DNA methylation alterations from the cancer genome atlas
DJ Weisenberger - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
… , and Illumina Infinium BeadArrays for DNA methylation profiling (1–3… This Review summarizes
the TCGA DNA methylation … types, the relationship between DNA methylation profiles and …
the TCGA DNA methylation … types, the relationship between DNA methylation profiles and …
A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution
… the atlas predicts a neuronal origin for schizophrenia, with neuron-specific differential DNA
methylation … In summary, the DNA methylation atlas enables the decomposition of 13 different …
methylation … In summary, the DNA methylation atlas enables the decomposition of 13 different …
Correlation patterns between DNA methylation and gene expression in the cancer genome atlas
… The role of DNA methylation in cancer is particularly well appreciated, with numerous … Atlas
(TCGA) have become readily accessible, our understanding of the role of DNA methylation …
(TCGA) have become readily accessible, our understanding of the role of DNA methylation …
A human DNA methylation atlas reveals principles of cell type-specific methylation and identifies thousands of cell type-specific regulatory elements
… Lastly, we applied the methylation atlas for analysis of methylomes obtained from
composite tissue samples and cfDNA. We developed a computational framework for labeling …
composite tissue samples and cfDNA. We developed a computational framework for labeling …
A comprehensive epigenome atlas reveals DNA methylation regulating skeletal muscle development
Y Yang, X Fan, J Yan, M Chen, M Zhu… - Nucleic acids …, 2021 - academic.oup.com
… Mechanistically, DNA methylation affected the … DNA methylation/SP1/IGF2BP3 axis in
skeletal myogenesis. Our results highlight the function and regulation of dynamic DNA methylation …
skeletal myogenesis. Our results highlight the function and regulation of dynamic DNA methylation …
Identification of DNA methylation-driven genes in esophageal squamous cell carcinoma: a study based on The Cancer Genome Atlas
T Lu, D Chen, Y Wang, X Sun, S Li, S Miao, Y Wo… - Cancer cell …, 2019 - Springer
… : normal DNA methylation data, cancer DNA methylation data and … methylated genes, which
named transcriptionally predictive genes, and compute the correlation between methylated …
named transcriptionally predictive genes, and compute the correlation between methylated …
Genomic and phenomic insights from an atlas of genetic effects on DNA methylation
Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to
understand mechanisms underpinning gene regulation and disease. Here we describe …
understand mechanisms underpinning gene regulation and disease. Here we describe …