Sensitive periods for the effect of childhood adversity on DNA methylation: results from a prospective, longitudinal study

EC Dunn, TW Soare, Y Zhu, AJ Simpkin… - Biological …, 2019 - Elsevier
… Exposure to early-life adversity is known to predict DNA methylation (DNAm) patterns that
may be related to psychiatric risk. However, few studies have investigated whether adversity

[HTML][HTML] Childhood adversity and DNA methylation in two population-based cohorts

LC Houtepen, R Hardy, J Maddock, D Kuh… - Translational …, 2018 - nature.com
childhood adversity (parental separation, parental mental or physical illness, child illness). …
between various types of childhood adversity and genome-wide DNA methylation in two large …

DNA methylation, behavior and early life adversity

M Szyf - Journal of Genetics and Genomics, 2013 - Elsevier
… Changes in DNA methylation in response to early life adversity are system wide Having
proven that alterations in DNA methylation in the brain in response to child adversity are not …

[HTML][HTML] Combined effects of genotype and childhood adversity shape variability of DNA methylation across age

D Czamara, E Tissink, J Tuhkanen, J Martins… - Translational …, 2021 - nature.com
Childhood adversity (CA), including child abuse and neglect, is a major risk factors for … DNA
methylation (DNAm) has been proposed as a biological process by which early-life adversity

Differential DNA methylation in peripheral blood mononuclear cells in adolescents exposed to significant early but not later childhood adversity

EA Esposito, MJ Jones, JR Doom… - Development and …, 2016 - cambridge.org
… in DNA methylation. Thus, we conducted an epigenome-wide association study to compare
DNA methylation … composition predicted using the DNA methylation data revealed a striking …

Childhood adversity and DNA methylation of genes involved in the hypothalamus–pituitary–adrenal axis and immune system: Whole-genome and candidate-gene …

J Bick, O Naumova, S Hunter, B Barbot… - Development and …, 2012 - cambridge.org
… We review evidence suggesting that changes in DNA methylation profiles of the genome …
genome-wide and candidate-gene DNA methylation profiles may inform hypotheses and guide …

The role of DNA methylation in the association between childhood adversity and cardiometabolic disease

G Hao, NA Youssef, CL Davis, S Su - International journal of cardiology, 2018 - Elsevier
… the effect of childhood adversity on DNA methylation status in genes related to the HPA
axis and immune system, and the possible mediation effects of DNA methylation in these two …

Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence

MJ Essex, W Thomas Boyce, C Hertzman… - Child …, 2013 - Wiley Online Library
child development were recruited to examine differences in DNA methylation in relation to
parent reports of adversity … within DNA derived from buccal epithelial cells showed differential …

[HTML][HTML] DNA methylation in healthy older adults with a history of childhood adversity—findings from the women 40+ healthy aging study

S Fiacco, ES Gardini, L Mernone, L Schick… - Frontiers in …, 2019 - frontiersin.org
childhood adversity would show higher methylation in the NR3C1 promoter and higher
methylation … of adversity would be differentially associated with methylation state and that greater …

[HTML][HTML] Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls

H Zhang, F Wang, HR Kranzler, H Zhao, J Gelernter - PLoS One, 2013 - journals.plos.org
… dependence (AD) seen in individuals with childhood adversity (CA) may result in part from
DNA methylation changes in AD patients, we examined peripheral blood DNA methylation