… in animal cell DNA was noted over 40 years ago, its role in the regulation of gene activity
has … The first indications that DNA methylation patterns of particular genes may indeed be …

… Transcriptional repression in vivo was relieved by the deacetylase inhibitor trichostatin A,
suggesting that two global mechanisms of gene regulation, DNA methylation and histone …

… methylation, we can evaluate DNA methylation in different genomic contexts: transcriptional
start sites with or without CpG islands, in gene … that the function of DNA methylation seems to …

… between DNA methylation, chromatin structure, and gene … association between DNA
methylation and expression than … about the role of DNA methylation in controlling gene …

… in a number of genes involved in DNA methylation has further … known to be involved in
DNA methylation has led to the … deacetylation, indicating that DNA methylation and histone …

… that DNA methylation was part of a system for controlling gene … function of DNA methylation
is permanent gene suppression … of genes. Box 1 lists data convincingly demonstrating that …

… In this review, we will discuss the basic function of DNA methylation in epigenetic gene
regulation, and further highlight its role in neural development and neurological disease. …

… -directed DNA methylation of fungal genes. Our data demonstrate that extant DNA methylation
… , and indicate that gene body methylation is an ancient property of eukaryotic genomes. …

… In summary, even the above short explanation of the DNA methylation-mediated gene
silencing clearly illustrates how all epigenetic components interact in a complex manner to …

… DNA methylation is an important regulator of gene … Alterations in DNA methylation are
common in a variety of tumors … regions of tumor suppressor genes leading to gene silencing, has …