DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons
KD Siegmund, CM Connor, M Campan, TI Long… - PloS one, 2007 - journals.plos.org
… Furthermore, we show that DNA methylation is dynamically regulated in differentiated …
Collectively, our results suggest that DNA methylation in the human cerebral cortex, including its …
Collectively, our results suggest that DNA methylation in the human cerebral cortex, including its …
DNA methylation signatures in development and aging of the human prefrontal cortex
S Numata, T Ye, TM Hyde, X Guitart-Navarro… - … Journal of Human …, 2012 - cell.com
… DNA methylation is strongly associated with genotypic variants … in brain development and
in de novo DNA methylation. Our results indicate that promoter DNA methylation in the human …
in de novo DNA methylation. Our results indicate that promoter DNA methylation in the human …
[HTML][HTML] DNA methylation signatures within the human brain
C Ladd-Acosta, J Pevsner, S Sabunciyan… - … Journal of Human …, 2007 - cell.com
… analyzed 76 brain samples representing cerebral cortex (n=35)… change in DNA methylation
(P<.004)—among brain regions. … that DNA methylation signatures distinguish brain regions …
(P<.004)—among brain regions. … that DNA methylation signatures distinguish brain regions …
Comprehensive DNA methylation and hydroxymethylation analysis in the human brain and its implication in mental disorders
… analysis of DNA methylation and hydroxymethylation in the human brain are summarized.
A … between the cerebral cortex and cerebellum were confirmed in an independent cohort. …
A … between the cerebral cortex and cerebellum were confirmed in an independent cohort. …
Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex
… In conclusion, the epigenetic landscape represented by DNA methylation in the human brain
varies markedly across development. Genetic loci implicated in risk for schizophrenia and …
varies markedly across development. Genetic loci implicated in risk for schizophrenia and …
Substantial DNA methylation differences between two major neuronal subtypes in human brain
… cell identity in the brain. To elucidate the role of DNA methylation in neuronal differentiation,
… the two major populations of human prefrontal cortex neurons—GABAergic interneurons …
… the two major populations of human prefrontal cortex neurons—GABAergic interneurons …
Distinct DNA methylation changes highly correlated with chronological age in the human brain
… age and DNA methylation level. Lastly, we show that the CpG sites where the DNA methylation
level is significantly associated with age are physically close to genes involved in DNA …
level is significantly associated with age are physically close to genes involved in DNA …
DNA methylation and its basic function
LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
… cells develop a stable and unique DNA methylation pattern that regulates tissue-… of
DNA methylation and demethylation in the nervous system. We will describe the DNA (de)methylation …
DNA methylation and demethylation in the nervous system. We will describe the DNA (de)methylation …
DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease
… DNA methylomes obtained from the cerebral cortex were used to identify aberrant DNA
methylation … comparison of the DNA methylation patterns in cerebral cortex and the rest of the …
methylation … comparison of the DNA methylation patterns in cerebral cortex and the rest of the …
Genome-wide divergence of DNA methylation marks in cerebral and cerebellar cortices
Y Xin, B Chanrion, MM Liu, H Galfalvy, R Costa… - PloS one, 2010 - journals.plos.org
… observe in DNA methylation in cerebellum and regions of the cerebral cortex may contribute
to … Our findings showing divergence of DNA methylation profiles in regions of cerebral cortex …
to … Our findings showing divergence of DNA methylation profiles in regions of cerebral cortex …
相关搜索
- dna methylation in the human brain
- differentiated neurons human cerebral cortex
- alzheimer's disease dna methylation
- dna methylation patterns
- dna methylation signatures
- role of dna methylation
- dna methylation differences
- dna methylation profiling
- dna methylation changes
- human frontal cortex mapping dna methylation
- dna methylation landscape developing human cortex
- population specificity human dna methylation
- dna methylation levels human chromosome
- healthy human aging dna methylation
- dna methylation impacts
- dynamic regulation of dna methylation