Epigenetic changes in Alzheimer's disease: decrements in DNA methylation

D Mastroeni, A Grover, E Delvaux, C Whiteside… - Neurobiology of …, 2010 - Elsevier
DNA methylation is a vital component of the … DNA methylation and eight methylation
maintenance factors in entorhinal cortex layer II, a region exhibiting substantial Alzheimer's disease (…

Dynamics of DNA methylation in aging and Alzheimer's disease

HA Irier, P Jin - DNA and cell biology, 2012 - liebertpub.com
… of DNA methylation in neurodegenerative diseases, with a special focus on DNA methylation
… context of neurodegeneration and its potential role in aging and Alzheimer's disease (AD). …

DNA methylation in Alzheimer's disease: In brain and peripheral blood

X Wei, L Zhang, Y Zeng - Mechanisms of Ageing and Development, 2020 - Elsevier
Alzheimer's disease (AD) is … DNA methylation is a vital component of the epigenetic
machinery which is the best-studied example covered by epigenetics. Studies of DNA methylation

[PDF][PDF] DNA methylation alterations in Alzheimer's disease

AS Yokoyama, JC Rutledge… - Environmental epigenetics, 2017 - academic.oup.com
DNA methylation, histone modifications and non-coding RNA, this review will focus specifically
on DNA methylation … in confirmed Alzheimer disease. Arch Neurol 1998;55: 1449–55. 41. …

Epigenetics in Alzheimer's disease: perspective of DNA methylation

TJ Qazi, Z Quan, A Mir, H Qing - Molecular Neurobiology, 2018 - Springer
… (FAD), and autosomal dominant Alzheimer’s disease (ADAD). Down to the minutest of …
methylation patterns like mitochondrial DNA methylation and ribosomal DNA (rDNA) methylation. …

Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain

N Coppieters, BV Dieriks, C Lill, RLM Faull… - Neurobiology of …, 2014 - Elsevier
DNA methylation (5-methylcytosine [5mC]) is one of several epigenetic markers altered
in Alzheimer's disease (AD) brain. More recently, attention has been given to DNA

DNA methylation variability in Alzheimer's disease

Z Huo, Y Zhu, L Yu, J Yang, P De Jager, DA Bennett… - Neurobiology of …, 2019 - Elsevier
DNA methylation plays a critical role in brain aging and Alzheimer's disease (AD). While …
largely focused on testing mean DNA methylation, DNA methylation instability (quantified by …

DNA methylation in the pathology of Alzheimer's disease: from gene to cognition

CH Poon, LSR Tse, LW Lim - Annals of the New York Academy …, 2020 - Wiley Online Library
… Among epigenetic modifications, DNA methylation requires … of DNA methylation, the effects
of aberrant methylation on gene … , as well as memory epigenetics in Alzheimer's disease. …

Global changes in DNA methylation in Alzheimer's disease peripheral blood mononuclear cells

A Di Francesco, B Arosio, A Falconi… - Brain, behavior, and …, 2015 - Elsevier
Alzheimer’s disease (AD). In this study we measured genome-wide DNA methylation by
luminometric methylation … of genome-wide DNA methylation, on DNA isolated from peripheral …

DNA methylation and Alzheimer's disease

T van Groen - Epigenetics of aging, 2010 - Springer
… the chances of developing Alzheimer’s disease. The decreased DNA methylation status with
… Furthermore, both the BACE and PS1 genes show similar decreased promoter methylation