Association of blood-based DNA methylation markers with late-onset Alzheimer disease: a potential diagnostic approach

B Acha, J Corroza, J Sánchez-Ruiz de Gordoa… - Neurology, 2023 - AAN Enterprises
… to identify novel noninvasive biomarkers for Alzheimer disease (AD) diagnosis. Recent …
DNA methylation marker panel as a noninvasive tool to identify patients with late-onset Alzheimer

DNA methylation and tag SNPs of the BDNF gene in conversion of amnestic mild cognitive impairment into Alzheimer's disease: a cross-sectional cohort study

B Xie, Z Liu, W Liu, L Jiang, R Zhang… - … of Alzheimer's …, 2017 - content.iospress.com
… The higher methylation levels at CpG5 site showed significant … The interaction between
DNA methylation of CpG5 and AA … The interactions between DNA methylation (CpG5) of the …

Alzheimer disease (AD) specific transcription, DNA methylation and splicing in twenty AD associated loci

C Humphries, MA Kohli, P Whitehead, DC Mash… - Molecular and Cellular …, 2015 - Elsevier
… in p-values was due to DNA methylation and not an artifact of the approach. Examination of
… We then compared the DNA methylation differences observed above in LOAD to disease

Genome-wide analysis of DNA methylation in an APP/PS1 mouse model of Alzheimer's disease

L Cong, J Jia, W Qin, Y Ren, Y Sun - Acta neurologica Belgica, 2014 - Springer
… To investigate aberrant genome-wide CpG methylation patterns in cortex brain tissue of APP…
novel disease-associated genes. This study investigates the genome-wide DNA methylation

Aberrant DNA methylation associated with Alzheimer's disease in the superior temporal gyrus

Z Gao, HJ Fu, LB Zhao, ZY Sun… - Experimental and …, 2018 - spandidos-publications.com
… Abnormal DNA methylation patterns have been demonstrated to be associated with the …
of Alzheimer's disease (AD). The present study aimed to identify differential methylation in the …

Altered mitochondrial DNA methylation and mitochondrial DNA copy number in an APP/PS1 transgenic mouse model of Alzheimer disease

YY Xu, LL Xu, M Han, XT Liu, F Li, XY Zhou… - Biochemical and …, 2019 - Elsevier
… Several researchers have investigated nuclear DNA methylation in AD samples, at either …
the nuclear DNA methylation, only two studies investigated mtDNA methylation changes in …

Impacts of DNA methylation on Tau protein related genes in the brains of patients with Alzheimer's disease

X Wei, P Du, Z Zhao - Neuroscience Letters, 2021 - Elsevier
… in abnormal Tau modification and aggregation in the development of Alzheimer's disease
… the effect of DNA methylation on tau protein in the brain of Alzheimer's disease patients and …

Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM in the blood of Japanese Alzheimer's disease patients

R Mitsumori, K Sakaguchi, D Shigemizu, T Mori… - PLoS …, 2020 - journals.plos.org
… -onset Alzheimer’s disease (AD) and DNA methylation levels in … We examined methylation
differences at CpG island shores in … and DNA methylomic profiling in Alzheimer's disease and …

Epigenomics of Alzheimer's disease

DA Bennett, L Yu, J Yang, HU Klein… - Translating Epigenetics to …, 2017 - Elsevier
DNA methylation data from large numbers of human brains. Here, we describe the basic
characteristics of DNA methylation … We observe that global DNA methylation features are well …

Alterations in global DNA methylation and hydroxymethylation are not detected in A lzheimer's disease

T Lashley, P Gami, N Valizadeh, A Li… - Neuropathology and …, 2015 - Wiley Online Library
… There is evidence suggesting an involvement of environmental factors in the pathogenesis
of Alzheimer's disease (AD), which prompted our study examining DNA methylation in this …