过去一年中添加的文章，按日期排序
Transdifferentiation occurs without resetting development-specific DNA methylation, a key determinant of full-function cell identity
A Radwan, J Eccleston, O Sabag, H Marcus… - Proceedings of the …, 2024 - pnas.org
2 天前 - … (WGBS), thus obtaining the full DNA methylation pattern both in the source cells as
well … in DNA methylation dynamics on promoter regions; however, methylation changes in …
well … in DNA methylation dynamics on promoter regions; however, methylation changes in …
Unraveling the mysteries of MGMT: Implications for neuroendocrine tumors
J Xu, S Ji, X Yu, J Chen - Biochimica et Biophysica Acta (BBA)-Reviews …, 2024 - Elsevier
2 天前 - … lead to the development of … methylation may elucidate the heterogeneity in treatment
response. CpG sites are of utmost importance in gene regulation through DNA methylation. …
response. CpG sites are of utmost importance in gene regulation through DNA methylation. …
Unravelling the impact of epigenetic mechanisms on offspring growth, production, reproduction and disease susceptibility
P Sindhu, A Magotra, V Sindhu… - Zygote (Cambridge … - pubmed.ncbi.nlm.nih.gov
2 天前 - … influencing development, reproduction and disease resistance. DNA methylation
patterns … modifications alter chromatin structure and affect DNA accessibility. Livestock-specific …
patterns … modifications alter chromatin structure and affect DNA accessibility. Livestock-specific …
Maternal Choline Supplementation as AaNutritional Intervention to Protect Against Mn-Induced Neurotoxicity
SL Howard - 2024 - escholarship.org
2 天前 - … gene expression and DNA methylation in the prefrontal … DNA methylation (172–176).
Since choline is a methyl donor and availability during development can alter methylation …
Since choline is a methyl donor and availability during development can alter methylation …
[HTML][HTML] Two-factor authentication underpins the precision of the piRNA pathway
M Dias Mirandela, A Zoch, J Leismann, S Webb… - Nature, 2024 - nature.com
2 天前 - … DNA methylation of young LINE1 elements. We propose that piRNA-directed
LINE1 DNA methylation … is erased and reset during germ cell development 14 . The piRNA …
LINE1 DNA methylation … is erased and reset during germ cell development 14 . The piRNA …
Molecular mechanisms for DNA methylation defects induced by ICF syndrome‐linked mutations in DNMT3B
CC Cho, CY Fei, BC Jiang, WZ Yang… - Protein …, 2024 - Wiley Online Library
3 天前 - … DNA methyltransferase 3B (DNMT3B) plays a crucial role in DNA methylation
during mammalian development. Mutations in DNMT3B are associated with human genetic …
during mammalian development. Mutations in DNMT3B are associated with human genetic …
Two-factor authentication underpins the precision of the piRNA pathway
MD Mirandela, A Zoch, J Leismann, S Webb… - Nature - pubmed.ncbi.nlm.nih.gov
3 天前 - … of young, active transposons during germline development in male mice 1 … DNA
methylation of young LINE1 elements. We propose that piRNA-directed LINE1 DNA methylation …
methylation of young LINE1 elements. We propose that piRNA-directed LINE1 DNA methylation …
Functional analyses of TET2 in vivo and in vitro reveal endothelial-specific roles in interferon responses that are dysregulated in hyperglycaemia
HLH Green, H Sum, P Sinha, A Visnagri, AC Brewer - 2024 - researchsquare.com
3 天前 - … Endothelial dysfunction represents a critical early event in the development of …
DNA methylation [10]. Thus, the epigenetic modi ers that determine genomic DNA methylation …
DNA methylation [10]. Thus, the epigenetic modi ers that determine genomic DNA methylation …
Genome-wide DNA methylation profiles in the raphe nuclei of patients with autism spectrum disorder
K Iwata, K Nakabayashi, K Ishiwata, K Nakamura… - 2024 - researchsquare.com
3 天前 - … Current research highlights environmental factors and epigenetic processes, such
as DNA methylation, as crucial in ASD development. This study explored epigenetic modi …
as DNA methylation, as crucial in ASD development. This study explored epigenetic modi …
A Computational Approach to Exploring the Role of Chromatin Modifiers in Development and Disease
LM Bondhus - 2024 - escholarship.org
3 天前 - … is essential to supporting the development of therapeutics that … analysis of differential
DNA methylation that addresses this … This limitation we address in our development of a …
DNA methylation that addresses this … This limitation we address in our development of a …