DNA methylation landscapes: provocative insights from epigenomics
MM Suzuki, A Bird - Nature reviews genetics, 2008 - nature.com
… methylated, as are gene bodies and intergenic DNA. e | The DNA methylation landscape of
… that genes are separated by long tracts of DNA that contain transposable elements and their …
… that genes are separated by long tracts of DNA that contain transposable elements and their …
The DNA methylation landscape in cancer
… and advances to distinguish major and minor DNA methylation intermediates such as 5hmC
from 5mC [15,16], the field is building comprehensive maps of DNA methylation landscapes…
from 5mC [15,16], the field is building comprehensive maps of DNA methylation landscapes…
[HTML][HTML] Navigating the DNA methylation landscape of cancer
A Nishiyama, M Nakanishi - Trends in Genetics, 2021 - cell.com
… DNA methylation patterns are maintained by the daughter DNA through a maintenance
DNA methylation … Both de novo DNA methylation and maintenance DNA methylation are …
DNA methylation … Both de novo DNA methylation and maintenance DNA methylation are …
Charting a dynamic DNA methylation landscape of the human genome
… In this study, we systematically investigated the DNA methylation state of most human … On
a global scale, human ES cells and their derivatives exhibit the highest DNA methylation levels…
a global scale, human ES cells and their derivatives exhibit the highest DNA methylation levels…
The DNA methylation landscape of advanced prostate cancer
… DNA methylation is a key regulator of gene expression, the comprehensive methylation
landscape of … We also identified intergenic regions where methylation is associated with RNA …
landscape of … We also identified intergenic regions where methylation is associated with RNA …
DNA methylation landscapes of human fetal development
RC Slieker, MS Roost, L van Iperen… - PLoS …, 2015 - journals.plos.org
… Here, we report on the DNA methylation landscape using the 450k array of four human …
-scale remodelling of DNA methylation from W9 to W22. Gain of DNA methylation preferentially …
-scale remodelling of DNA methylation from W9 to W22. Gain of DNA methylation preferentially …
The DNA methylation landscape of human early embryos
H Guo, P Zhu, L Yan, R Li, B Hu, Y Lian, J Yan, X Ren… - Nature, 2014 - nature.com
DNA methylation is a crucial element in the epigenetic regulation of mammalian embryonic
development 1 , 2 , 3 , 4 , 5 . However, its dynamic patterns have not been analysed at the …
development 1 , 2 , 3 , 4 , 5 . However, its dynamic patterns have not been analysed at the …
An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging
… Importantly, we demonstrate the feasibility of integrating Illumina 450k DNA methylation
with ENCODE data to identify transcription factors with key roles in cellular development and …
with ENCODE data to identify transcription factors with key roles in cellular development and …
Neuronal activity modifies the DNA methylation landscape in the adult brain
… Activity-induced modification of neuronal DNA methylome … modifies the landscape of
neuronal DNA methylation in vivo, we took a genome-wide approach to profile the DNA methylome …
neuronal DNA methylation in vivo, we took a genome-wide approach to profile the DNA methylome …
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
… of DNA methylation sequencing in large cohorts of routinely collected clinical FFPE tumor
samples. To put the DNA methylation data … us to identify DNA methylation patterns predictive of …
samples. To put the DNA methylation data … us to identify DNA methylation patterns predictive of …