[HTML][HTML] The genome-wide landscape of DNA methylation and hydroxymethylation in response to sleep deprivation impacts on synaptic plasticity genes

R Massart, M Freyburger, M Suderman… - Translational …, 2014 - nature.com
… on the epigenetic landscape of the cerebral cortex, with DNA methylation and hydroxymethylation
… Neuronal activity modifies the DNA methylation landscape in the adult brain. Nature …

[HTML][HTML] The DNA methylation landscape of Chinese hamster ovary (CHO) DP-12 cells

A Wippermann, O Rupp, K Brinkrolf, R Hoffrogge… - Journal of …, 2015 - Elsevier
… In this study the DNA methylation landscape of IgG-producing CHO DP-12 cells was
characterized and putative influences of the methylation landscape on gene expression were …

[HTML][HTML] Novel genome-wide DNA methylation profiling reveals distinct epigenetic landscape, prognostic model and cellular composition of early-stage lung …

J Gan, M Huang, W Wang, G Fu, M Hu, H Zhong… - Journal of Translational …, 2024 - Springer
… This study firstly delves into novel pattern of epigenomic DNA methylation and provides a
multidimensional analysis of the role of DNA methylation revealed by EM-seq in early-stage …

[HTML][HTML] Human body epigenome maps reveal noncanonical DNA methylation variation

MD Schultz, Y He, JW Whitaker, M Hariharan… - Nature, 2015 - nature.com
… Surveys of DNA methylation in human tissues have established a complex landscape … To
understand the variability of DNA methylation across human tissues better, we obtained post-…

[HTML][HTML] Pan-cancer analysis of frequent DNA co-methylation patterns reveals consistent epigenetic landscape changes in multiple cancers

J Zhang, K Huang - Bmc Genomics, 2017 - Springer
… The genome-wide DNA methylation pattern (DNA methylome) is affected by cell … DNA
methylation pattern is a hallmark of cancer [3], and it has been speculated that DNA methylation

[PDF][PDF] Reversible regulation of promoter and enhancer histone landscape by DNA methylation in mouse embryonic stem cells

AD King, K Huang, L Rubbi, S Liu, CY Wang, Y Wang… - Cell reports, 2016 - cell.com
… observed in DNA methylation null mESCs … DNA methylation shapes the histone landscape
and transcriptome in mESCs. To study this, we employed sets of mESC with fully methylated

The Role of the Genetic Code in the DNA Methylation Landscape Formation

H Heyn - Epigenomics in Health and Disease, 2016 - Elsevier
… factors in shaping the DNA methylation landscape during differentiation processes. …
methylation gives valuable mechanistic insights into the dynamics and flexibility of DNA methylation

The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes

RC Poulos, J Olivier, JWH Wong - Nucleic acids research, 2017 - academic.oup.com
… between methylation and common mutation and repair processes, with these mechanisms
defining a key part of the mutational landscapeDNA methylation is an epigenetic mark, most …

Genome-wide epigenetic landscape of lung adenocarcinoma links HOXB9 DNA methylation to intrinsic EGFR-TKI resistance and heterogeneous responses

SF Su, CH Liu, CL Cheng, CC Ho, TY Yang… - JCO Precision …, 2021 - ascopubs.org
… We conducted genome-wide DNA methylation profiling of tumors from patients before their
… a DNA methylation landscape to elucidate the association of DNA methylation with the EGFR-…

Dynamics and context-dependent roles of DNA methylation

C Ambrosi, M Manzo, T Baubec - Journal of molecular biology, 2017 - Elsevier
… on general features of DNA methylation and how … DNA methylation landscapes during early
mouse developmental stages and in neurons as a comparison. Shown are DNA methylation