… However, there are still huge research gaps regarding the DNA methylation status of
confirmed risk gene loci. Future research focused on elucidating the epigenetic status of these …

… and Alzheimer's disease (AD). While prior studies have largely focused on testing mean
DNA methylation, DNA methylation instability (… GWAS loci enrichment is shown in Table S8. …

… We found that the level of methylation at 71 of the 415,848 … We validated 11 of the differentially
methylated regions in an … Our analyses suggest that these DNA methylation changes …

… Alzheimer's disease (AD) is the most widespread neurodegenerative … methylated loci (DMLs)
or differentially hydro-methylated loci (DhMLs). With the development of DNA methylation …

… 0.98, P < 2.2e −16 ) and hence a methylation quantitative trait locus (mQTL) in cis (Fig. 1C), …
, logical memory delayed recall, Alzheimer Disease Assessment Scale-Cognitive Subscale …

… 28 gene loci associated with AD pathology. Of the 28 gene loci, DNA methylation of five genes
… Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. …

… d Distribution of differential DNA methylation marks across different genomic loci. … Data
collection and sharing for this project was funded by the Alzheimer's Disease Neuroimaging …

… in DNA methylation in the superior temporal gyrus of patients with Alzheimer’s disease,
highlighting novel loci that … and mechanisms underlying Alzheimer’s disease pathogenesis, and …

… and for aberrant DNA in cancer. To determine the feasibility of DNA methylation studies in
the … The global DNA methylation profile for these 2 loci is similar to that observed in the 5′ …

… While we observed DNA methylation differences across the 20 loci in LOAD, there was
only a slight difference in promoter based methylation and expression. Our findings replicated …