… -wide methylation loss is associated with both concordant loss of … loss of allelic replication
timing in cancer hypomethylation models, potentially through the gene deregulation of DNA …

… The DNA methylation imbalance in p53-deficient (… DNA methylation as well as increased
methylation landscape heterogeneity. In differentiating p53 −/− mESCs, elevated methylation …

… At this time, knockout embryos exhibit a two-thirds loss of DNA methylation, in addition to
numerous apoptotic cells in a variety of developing tissues including the brain. Interestingly, …

… Although we find no evidence of hemizygous loss of these genes in RER + tumors,
alternative mechanism such as hypermethylation appear to play an important role in hMLH1 …

… The lack of access to the nucleus by the maintenance Dnmt leads to a loss of DNA methylation
of the maternal genome such that the parental genomes become almost equally low in …

… The difference between gain or loss of DNA methylation was not only quantitative, but also
qualitative. CpG hypermethylation events in the colorectal cancer cells mostly occurred in …

… of imprinting (LOI) is the disruption of imprinted epigenetic marks through gain or loss of DNA
methylation, or simply the loss of normal allele-specific gene expression 28 . Studies of LOI …

… a progressive loss of DNA methylation with each cell division and that this loss of methylation
… This loss of DNA methylation could occur as these resting zone chondrocytes gradually …

… This loss of DNA methylation is associated with reduced expression of the maintenance …
This large-scale loss of DNA methylation in the CC leads to the reactivation of TEs as well as to …

… Given this finding of substantial loss of DNA methylation accompanying differentiation, we
are in a unique position to ask whether it has a role in the changes in gene expression that …