Genetic alterations of DNA methylation machinery in human diseases

T Hamidi, AK Singh, T Chen - Epigenomics, 2015 - Taylor & Francis
… In this review, we focus our discussion on genetic alterations in components of the DNA
methylation machinery. While the mechanisms by which most of these mutations contribute to …

Regulation of the DNA methylation machinery and its role in cellular transformation

M Szyf, N Detich - 2001 - Elsevier
… of the DNA methylation machinery responsible for replicating the DNA methylation pattern…
Recent data have changed our basic understanding of the DNA methylation machinery. A …

The DNA methylation machinery as a therapeutic target

M Szyf - Current Drug Targets, 2000 - ingentaconnect.com
DNA methylation plays an important role in the control of genomic processes, suggests how
the DNA methylation machinery … manipulate the DNA methylation machinery and discusses …

DNA methylation and its basic function

LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
… a stable and unique DNA methylation pattern that regulates tissue-… of DNA methylation
and demethylation in the nervous system. We will describe the DNA (de)methylation machinery

Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation

L Schermelleh, A Haemmer, F Spada… - Nucleic acids …, 2007 - academic.oup.com
… of the replication machinery. We investigated how the slow and discontinuous DNA
methylation could be mechanistically linked with fast and processive DNA replication. Using …

DNA methylation and imprinting in plants: machinery and mechanisms

PRV Satyaki, M Gehring - Critical reviews in biochemistry and …, 2017 - Taylor & Francis
… between differential DNA methylation and imprinted gene expression in plants. We summarize
the protein machinery and processes that determine endosperm methylation patterns and …

DNA methylation machinery in the endometrium and endometrial cancer

V Caplakova, E Babusikova, E Blahovcova… - Anticancer …, 2016 - ar.iiarjournals.org
… Components of DNA methylation machinery in relation to the menstrual cycle. The proteins
of DNA methylation machinery can be divided into three groups: writers, erasers and readers. …

Controlling DNA methylation: many roads to one modification

M Freitag, EU Selker - Current opinion in genetics & development, 2005 - Elsevier
DNA methylation machinery (Table 1). Histone deacetylation might act both upstream and
downstream of histone and DNA methylation. … of methylation at H3 K4 preceded methylation of …

Targeting DNA methylation in cancer

M Szyf - Ageing research reviews, 2003 - Elsevier
… We now understand that DNA methylation machineries might include a number of … the DNA
methylation machinery as anticancer agents. This review discusses the possible role of DNA

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery

T Guastafierro, B Cecchinelli, M Zampieri… - Journal of Biological …, 2008 - ASBMB
DNA methylation machinery; the DNA methyltransferase activity is inhibited with consequences
for the methylation … affecting centromeric minor satellite and B1 DNA repeats. In vitro data …