Genetic alterations of DNA methylation machinery in human diseases
T Hamidi, AK Singh, T Chen - Epigenomics, 2015 - Taylor & Francis
… In this review, we focus our discussion on genetic alterations in components of the DNA
methylation machinery. While the mechanisms by which most of these mutations contribute to …
methylation machinery. While the mechanisms by which most of these mutations contribute to …
Regulation of the DNA methylation machinery and its role in cellular transformation
M Szyf, N Detich - 2001 - Elsevier
… of the DNA methylation machinery responsible for replicating the DNA methylation pattern…
Recent data have changed our basic understanding of the DNA methylation machinery. A …
Recent data have changed our basic understanding of the DNA methylation machinery. A …
The DNA methylation machinery as a therapeutic target
M Szyf - Current Drug Targets, 2000 - ingentaconnect.com
… DNA methylation plays an important role in the control of genomic processes, suggests how
the DNA methylation machinery … manipulate the DNA methylation machinery and discusses …
the DNA methylation machinery … manipulate the DNA methylation machinery and discusses …
DNA methylation and its basic function
LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
… a stable and unique DNA methylation pattern that regulates tissue-… of DNA methylation
and demethylation in the nervous system. We will describe the DNA (de)methylation machinery …
and demethylation in the nervous system. We will describe the DNA (de)methylation machinery …
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Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation
L Schermelleh, A Haemmer, F Spada… - Nucleic acids …, 2007 - academic.oup.com
… of the replication machinery. We investigated how the slow and discontinuous DNA
methylation could be mechanistically linked with fast and processive DNA replication. Using …
methylation could be mechanistically linked with fast and processive DNA replication. Using …
DNA methylation and imprinting in plants: machinery and mechanisms
PRV Satyaki, M Gehring - Critical reviews in biochemistry and …, 2017 - Taylor & Francis
… between differential DNA methylation and imprinted gene expression in plants. We summarize
the protein machinery and processes that determine endosperm methylation patterns and …
the protein machinery and processes that determine endosperm methylation patterns and …
DNA methylation machinery in the endometrium and endometrial cancer
V Caplakova, E Babusikova, E Blahovcova… - Anticancer …, 2016 - ar.iiarjournals.org
… Components of DNA methylation machinery in relation to the menstrual cycle. The proteins
of DNA methylation machinery can be divided into three groups: writers, erasers and readers. …
of DNA methylation machinery can be divided into three groups: writers, erasers and readers. …
Controlling DNA methylation: many roads to one modification
… DNA methylation machinery (Table 1). Histone deacetylation might act both upstream and
downstream of histone and DNA methylation. … of methylation at H3 K4 preceded methylation of …
downstream of histone and DNA methylation. … of methylation at H3 K4 preceded methylation of …
Targeting DNA methylation in cancer
M Szyf - Ageing research reviews, 2003 - Elsevier
… We now understand that DNA methylation machineries might include a number of … the DNA
methylation machinery as anticancer agents. This review discusses the possible role of DNA …
methylation machinery as anticancer agents. This review discusses the possible role of DNA …
CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery
T Guastafierro, B Cecchinelli, M Zampieri… - Journal of Biological …, 2008 - ASBMB
… DNA methylation machinery; the DNA methyltransferase activity is inhibited with consequences
for the methylation … affecting centromeric minor satellite and B1 DNA repeats. In vitro data …
for the methylation … affecting centromeric minor satellite and B1 DNA repeats. In vitro data …