Long-term ambient particle exposures and blood DNA methylation age: findings from the VA normative aging study

JC Nwanaji-Enwerem, E Colicino… - Environmental …, 2016 - academic.oup.com
… with DNA methylation age (DNAm-age), an epigenome-wide DNA methylation based … of
589 older men participating in the VA Normative Aging Study with 1–3 visits between 2000 and …

DNA methylation and healthy human aging

MJ Jones, SJ Goodman, MS Kobor - Aging cell, 2015 - Wiley Online Library
… In addition to normal DNA methylation, variations and derivatives of the methyl mark on
CpG dinucleotides have also been reported, including hydroxymethyl, formyl, and carboxyl …

Genome-wide analysis of DNA methylation and fine particulate matter air pollution in three study populations: KORA F3, KORA F4, and the normative aging study

T Panni, AJ Mehta, JD Schwartz… - Environmental …, 2016 - ehp.niehs.nih.gov
… We studied the association between DNA methylation and short- and mid-term air pollution
exposure using genome-wide data and identified potential biological pathways for additional …

Psychological factors and DNA methylation of genes related to immune/inflammatory system markers: the VA Normative Aging Study

D Kim, LD Kubzansky, A Baccarelli, D Sparrow… - BMJ open, 2016 - bmjopen.bmj.com
… In this study of community-dwelling elderly adult men, we found consistent associations …
factors, with higher average leucocyte DNA methylation in ICAM-1 promoter regions and in F3 …

Air pollution and DNA methylation: interaction by psychological factors in the VA Normative Aging Study

J Madrigano, A Baccarelli, MA Mittleman… - American journal of …, 2012 - academic.oup.com
… Few studies have examined the association between air pollution and DNA methylation, and
none… the interrelation among air pollution, psychological factors, and DNA methylation. This …

[HTML][HTML] DNA methylation of oxidative stress genes and cancer risk in the Normative Aging Study

T Gao, BT Joyce, L Liu, Y Zheng, Q Dai… - … of Cancer Research, 2016 - ncbi.nlm.nih.gov
… In this study, we examined the prospective association between blood DNA methylation of
four oxidative stress genes and cancer incidence. Our study population included a total of 582 …

Smoking-related DNA methylation is associated with DNA methylation phenotypic age acceleration: The veterans affairs normative aging study

Y Yang, X Gao, AC Just, E Colicino, C Wang… - … environmental research …, 2019 - mdpi.com
Study Subjects This study included 692 participants from the Normative Aging Study (NAS),
a closed longitudinal study of aging in men from eastern Massachusetts [16]. A total of 1596 …

Repetitive element DNA methylation and circulating endothelial and inflammation markers in the VA normative aging study

A Baccarelli, L Tarantini, RO Wright, V Bollati… - Epigenetics, 2010 - Taylor & Francis
… Mechanisms linking DNA hypomethylation to increased cardiovascular risk … elderly individuals,
we evaluated whether DNA methylation in LINE-1 repetitive element, heavily methylated

DNA methylation in cancer and aging

M Klutstein, D Nejman, R Greenfield, H Cedar - Cancer research, 2016 - AACR
DNA methylationnormal DNA methylation patterns and understanding how this stable
epigenetic mark works to prevent gene activation during development. Aberrant DNA methylation

[HTML][HTML] … individuals: an analysis of DNA methylation age metrics, leukocyte telomere length, and mitochondrial DNA copy number in the VA normative aging study

J Dolcini, H Wu, JC Nwanaji-Enwerem… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
aging. Thus, we extend upon our previous study and utilized data from the VA Normative
Aging Study (NAS) cohort to examine the prospective associations of mtDNAcn with four aging