DNA methylation and breast cancer

M Szyf, P Pakneshan, SA Rabbani - Biochemical pharmacology, 2004 - Elsevier
… This view of the DNA methylation pattern has implications on our understanding of how DNA
methylation patterns are disrupted in cancer and DNA methylation targeted therapy. Thus, it …

Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns

K Holm, C Hegardt, J Staaf, J Vallon-Christersson… - Breast cancer …, 2010 - Springer
… A reason for this discrepancy could be our finding of characteristic methylation patterns for
the breast cancer subtypes. As sporadic tumours, lymph node-positive and negative tumours …

DNA methylation in breast cancer.

X Yang, L Yan, NE Davidson - Endocrine-related cancer, 2001 - erc.bioscientifica.com
cancer types. This review will briefly discuss basic aspects of DNA methylation, recent
advances in DNA … of gene transcriptional regulation built on methylated CpGs. In particular, we …

DNA methylation signatures for breast cancer classification and prognosis

M Szyf - Genome medicine, 2012 - Springer
breast cancer and other diseases. Here, I review the scientific basis for … DNA methylation
signatures in breast cancer classification and prognosis. I discuss the role of DNA methylation

DNA methylation profiles capturing breast cancer heterogeneity

X Chen, J Zhang, X Dai - BMC genomics, 2019 - Springer
… Through comparisons on differentially methylated CpG sites among breast cancer subtypes
… genes, whose methylation pattern identifies the triple negative breast cancer subtype, and …

Cell type-specific DNA methylation patterns in the human breast

N Bloushtain-Qimron, J Yao… - Proceedings of the …, 2008 - National Acad Sciences
… To further test the hypothesis that the epigenetic profiles defining progenitor-like cells are
distinct in different breast cancer subtypes, we analyzed the methylation of PACAP, FOXC1, …

Array-based DNA methylation profiling for breast cancer subtype discrimination

I Van der Auwera, W Yu, L Suo, L Van Neste… - PloS one, 2010 - journals.plos.org
breast cancer (IBC) phenotype is characterized by a specific DNA methylation pattern. IBC
… of primary epithelial breast tumors and affects ∼5% of women with breast cancer [18], [19]. …

Specific breast cancer prognosis‐subtype distinctions based on DNA methylation patterns

S Zhang, Y Wang, Y Gu, J Zhu, C Ci, Z Guo… - Molecular …, 2018 - Wiley Online Library
DNA methylation is an important regulator of gene … based on DNA methylation status using
669 breast cancers from the … The specific DNA methylation patterns were reflected by different …

DNA methylation and breast cancer: A way forward

MT Vietri, G D'elia, G Benincasa… - International …, 2021 - spandidos-publications.com
… clinical value of DNA methylation in liquid biopsy were reported. DNA methylation patterns
may be used as a biomarker for the risk and survival prognosis of patients with cancer. …

[HTML][HTML] DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables

S Kamalakaran, V Varadan, HEG Russnes, D Levy… - Molecular …, 2011 - Elsevier
… that DNA methylation patterns in the breast cancer subtypes are not limited only to cancer-…
et al., determined DNA methylation profiles in 33 familial breast cancer samples. This study …