过去一年中添加的文章,按日期排序

Whole Genome Sequencing and single-cell transcriptomics identify KMT2D as a potential new driver for pituitary adenomas

M Brunner, J Meylan-Merlini, M Muriset, S Oreshkov… - medRxiv, 2024 - medrxiv.org
2 天前 - DNA methylation differences between this tumor and other somatotroph tumors. …
tumor, consistently showed lower overall methylation profiles compared to the other tumor types…

Uncovering epigenetic heterogeneity in hepatocellular carcinoma

Y Ajouaou, KC Sadler - Hepatology - journals.lww.com
3 天前 - … , DNA methylation profilesDNA methylation is a significant epigenetic mark, it is
only one of many. The vast complexity of the epigenome cannot be reduced to DNA methylation

Unravelling the impact of epigenetic mechanisms on offspring growth, production, reproduction and disease susceptibility

P Sindhu, A Magotra, V Sindhu… - Zygote (Cambridge … - pubmed.ncbi.nlm.nih.gov
3 天前 - DNA methylation patterns silence gene expression by blocking transcription factor
binding, while histone modifications alter chromatin structure and affect DNAprofiling that …

[HTML][HTML] A machine learning-based method for feature reduction of methylation data for the classification of cancer tissue origin

MA De Velasco, K Sakai, S Mitani, Y Kura… - International Journal of …, 2024 - Springer
3 天前 - … Genome DNA methylation profiling is a promising yet costly method for cancer …
to identify cancer types using methylation profiles from a limited number of CpG sites. …

The aging paradox: integrating biological, genetic, epigenetic, and aesthetic insights into skin aging and non-surgical interventions

WR Webb, P Rao, JDA Carruthers, Z Rahman… - European Journal of …, 2024 - Springer
3 天前 - … and epigenetic mechanisms, such as DNA methylation and microRNA regulation,
in … , integrating genetic and epigenetic profiling to tailor treatments to individual needs. …

[HTML][HTML] Genome-wide DNA methylation sequencing reveals the involvement of ferroptosis in hepatotoxicity induced by dietary exposure to food-grade titanium …

J Shang, J Yan, H Lou, R Shou… - Particle and …, 2024 - particleandfibretoxicology …
3 天前 - … To explore the role of DNA methylation regulation in E 171-induced potential
ferroptosis, we examined the DNA methylation profiles of Ncoa4, Sqstm1, and Map1lc3b, the key …

[HTML][HTML] Methylation alterations of imprinted genes in different placental diseases

X Wang, Y Liu, Y Wu, C Lin, S Yang, Y Yang, D Chen… - Clinical …, 2024 - Springer
3 天前 - … suggested that DNA methylation and expression of imprinted genes are aberrant
in both PE and PAS placentas and that PE and PAS have different methylation profiles, which …

Odontogenic Myxomas Harbor Recurrent Copy Number Alterations and a Distinct Methylation Signature

TG Kleijn, B Ameline, WH Schreuder… - The American Journal …, 2024 - journals.lww.com
3 天前 - … formed a distinct DNA methylation class. Copy number profiling showed recurrent
whole-… copy number patterns and a distinct DNA methylation profile, which can be used as an …

Genome-wide DNA methylation profiles in the raphe nuclei of patients with autism spectrum disorder

K Iwata, K Nakabayashi, K Ishiwata, K Nakamura… - 2024 - researchsquare.com
3 天前 - … We comprehensively analyzed genome-wide DNA methylation pro les in the dorsal
raphe brain region using the In nium HumanMethylation450 BeadChip (Illumina). In addition…

[HTML][HTML] DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life

D Martino, N Kresoje, N Amenyogbe… - Nature …, 2024 - nature.com
4 天前 - … To determine the cell-type specificity of this ontogeny signature, we deconvoluted
whole blood methylation profiles from each cohort into inferred immune cell ratios and …