… DNA methylation status at enhancers is an important determinant of enhancer–promoter
interactions 32 , signifying that DNA methylation … With this model, we used our enhancer CpH …

… The relationship between DNA methylation and … investigated by modeling a linear regression
(DNA methylation as … , adjusting the model as conducted in the DNA methylation differential …

… biomarker of aging based on DNA methylation (DNAm) levels [11], … models, we then
examined the association between DNAm age and cognitive functioning by AD dementia status …

… We found four DMPs showing higher levels of DNA methylation … Alzheimers disease (AD)
is a chronic neurodegenerative … Within this set of 118 DMPs, we fitted a linear model adjusted …

… changed in pace with age [27] and that hypomethylation was occurring in PASG mutant
mice, a model of aging [28]. However, the results of the present study suggested that there is no …

… was modeled with a generalized linear model using the DSS software, an implementation
of the beta-binomial model designed for DNA methylation analysis. Cell-type proportions for …

… of Alzheimer’s disease (AD). This study aimed to evaluate whether altered DNA methylation
status of … to the multivariate Cox proportional hazard model. The results indicated that higher …

… To account for technical variation, we also tested models adjusted for white blood cell
abundance (plasmablasts, +CD8pCD28nCD45RA-T cells, naïve CD8 T cells, CD4 T cells, natural …

… IF as a modifier of the DNA methylation landscape in a pathological state. Here we show
that the DNA methylation landscape is altered in a CCH mouse model of VaD. Mapping of the …

… microglia is a means to model neurodegeneration in rodents [… been implicated in the course
of Alzheimer's disease (AD) [2]… region, we analyzed the DNA methylation status of healthy …