[HTML][HTML] An essential role for DNA methyltransferase DNMT3B in cancer cell survival

N Beaulieu, S Morin, IC Chute, MF Robert… - Journal of Biological …, 2002 - ASBMB
… In this report, we have investigated the role of DNMT3B in the aberrant methylation and
inactivation of genes in human tumor cells as well as its role in the maintenance of the …

DNMT3B gene amplification predicts resistance to DNA demethylating drugs

L Simó‐Riudalbas, SA Melo… - … and Cancer, 2011 - Wiley Online Library
… breast cancer cells undergo gene amplification of the DNA … are less sensitive to the decrease
in cell viability caused by 5-… for the maintenance of DNA methylation patterns in adult cells, …

DNA methyltransferase 3b (DNMT3b), tumor tissue DNA methylation, Gleason score, and prostate cancer mortality: investigating causal relationships

A Gillio-Tos, V Fiano, D Zugna, L Vizzini… - Cancer Causes & …, 2012 - Springer
DNA methyltransferase (DNMT) genotype, DNA methylation, Gleason score, and mortality
in two cohorts of prostate cancer … The association between DNMT and cancer survival has …

DNA methyltransferase DNMT3b protein overexpression as a prognostic factor in patients with diffuse large B‐cell lymphomas

K Amara, S Ziadi, M Hachana, N Soltani… - Cancer …, 2010 - Wiley Online Library
… overall survival (P = 0.004) and progression-free survival (P = … of DNMT1 and DNMT3b
expression in cancer development and … DNMT3b overexpression was associated with cancer cell

DNA methylation by DNMT1 and DNMT3b methyltransferases is driven by the MUC1-C oncoprotein in human carcinoma cells

H Rajabi, A Tagde, M Alam, A Bouillez, S Pitroda… - Oncogene, 2016 - nature.com
… patterns are associated with carcinogenesis and cancer cell survival. The oncogenic
MUC1-C protein is aberrantly overexpressed in diverse carcinomas; however, there is no known …

The role of DNA methyltransferase 3b in esophageal squamous cell carcinoma

MF Chen, MS Lu, PY Lin, PT Chen, WC Chen… - Cancer, 2012 - Wiley Online Library
DNA methyltransferase 3b (DNMT3b) in esophageal squamous … -Meier overall survival
curves indicate that the DNMT3b-… suppressed DNMT3b expression in esophageal cancer cells

Nanaomycin A selectively inhibits DNMT3B and reactivates silenced tumor suppressor genes in human cancer cells

D Kuck, T Caulfield, F Lyko, JL Medina-Franco - Molecular cancer …, 2010 - AACR
… DNMT3A and DNMT3B are de novo methyltransferases … of DNA methylation patterns in
normal and tumor cells has … are important mechanisms through which tumor cells can survive (7). …

Histone deacetylase inhibitors inducing human cervical cancer cell apoptosis by decreasing DNA-methyltransferase 3B

LIU Ning, L Zhao, X Li, J Wang, G Chai… - Chinese medical …, 2012 - journals.lww.com
… and obviously decrease DNMT3B expressionin Hela and Caski cells. We … cancer cell
apoptosis by decreasing DNMT3B and Whether DNMT3B was important for cancer cell survival. To …

[HTML][HTML] High DNA Methyltransferase DNMT3B Levels: A Poor Prognostic Marker in Acute Myeloid Leukemia

S Hayette, X Thomas, L Jallades, K Chabane… - PloS one, 2012 - journals.plos.org
… of DNMT3B/3B NC is an independent predictor of poor survival in AML. Its … cancer cells
acquire alteration in DNA methylation is unknown but aberrant transcription of the DNMT3B

Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas

G Rajendran, K Shanmuganandam, A Bendre… - Journal of neuro …, 2011 - Springer
cancer cells. The enhanced expression of DNMT1 is responsible for abnormal methylation
patterns of TSGs in colon cancer [… leading to cancel cell survival is shown for HCT116 cells [41…