Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer

J Yang, X Wei, Q Wu, Z Xu, D Gu… - Molecular …, 2011 - spandidos-publications.com
… that DNMTs were overexpressed in gastric cancer tissues. Although overexpression of
DNMTs is not equal to the aberrant DNA methylation pattern in gastric cancer, our findings, such …

The expression and clinical significance of DNA methyltransferase proteins in human gastric cancer

WJ Ding, JY Fang, XY Chen, YS Peng - Digestive diseases and sciences, 2008 - Springer
… This study investigates the varied expression of DNA methyltransferase (DNMT) proteins
in gastric cancer (GC) and their relationship with the biological behavior of the tissues. …

DNA methylation as a molecular biomarker in gastric cancer

T Tahara, T Arisawa - Epigenomics, 2015 - Taylor & Francis
DNA methylation plays a significant role in gastric carcinogenesis. The CpG island …
subtypes of gastric cancer (GC) and the relationship between specific methylation patterns and …

Accumulation of DNA methylation is associated with tumor stage in gastric cancer

N Oue, Y Mitani, J Motoshita… - Cancer …, 2006 - Wiley Online Library
… In this study, we investigated DNA methylation of 12 tumor-related genes, of which only 2, …
involved in tumor invasion or metastasis.56, 57 In the present study, DNA methylation of CDH1 …

DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer

K Mutze, R Langer, F Schumacher, K Becker… - … journal of cancer, 2011 - Elsevier
… may influence the effect of DNA-damaging drugs. We examined the prognostic and predictive
impact of DNA methyltransferase (DNMT) 1 and 3b expression in gastric carcinomas (GC) …

… DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG …

T Etoh, Y Kanai, S Ushijima, T Nakagawa… - The American journal of …, 2004 - Elsevier
… Examples of PCR products from DNA methylation analyses of multiple CpG islands in
patients with gastric cancer (S). N, noncancerous mucosae; T, cancer tissue. The …

[PDF][PDF] Alteration of DNA methylation in gastric cancer with chemotherapy

SJ Choi, SW Jung, S Huh, YS Chung… - … of microbiology and …, 2017 - scholar.archive.org
… to the DNA methylation status in gastric cancers that had been … DNA methylation in gastric
cancers treated with 5-FU. We … - or hypomethylated following gastric cancer treatment with 5-…

MiR-148a regulates MEG3 in gastric cancer by targeting DNA methyltransferase 1

J Yan, X Guo, J Xia, T Shan, C Gu, Z Liang, W Zhao… - Medical oncology, 2014 - Springer
… MiR-148a can suppress gastric tumorigenesis through regulating the expression of … as
DNA methyltransferase 1(DNMT-1). We examined the expression of MEG3 in 52 gastric cancer

[HTML][HTML] DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis

GH Kang, S Lee, NY Cho, T Gandamihardja… - Laboratory …, 2008 - Elsevier
carcinoma (GC) is one of the tumors with a high frequency of … In this study, we prescreened
DNA methylation of 170 CpG … 27 DNA methylation markers showing higher methylation

DNA methyltransferases and gastric cancer: insight into targeted therapy

S Fattahi, M Golpour, F Amjadi-Moheb… - …, 2018 - Taylor & Francis
… importance of DNA methylation in gastric cancer progression, anticancer drug sensitivity
and gastric cancer patient survival, DNMTis can be useful in promoting the quality of treatment. …