Spectroscopy and molecular docking analysis reveal structural specificity of flavonoids in the inhibition of α-glucosidase activity
J Liu, Y Kong, J Miao, X Mei, S Wu, Y Yan… - International journal of …, 2020 - Elsevier
… The human α-glucosidase (C-terminal maltase-glucoamylase, GH31) was used in the …
docking analysis to determine the interaction of eriocitrin and eriodictyol with the α-glucosidase. …
docking analysis to determine the interaction of eriocitrin and eriodictyol with the α-glucosidase. …
Exploring the structure–activity relationship and interaction mechanism of flavonoids and α-glucosidase based on experimental analysis and molecular docking …
H Tang, L Huang, C Sun, D Zhao - Food & function, 2020 - pubs.rsc.org
α-Glucosidase (AG) has always been an indispensable drug target for the treatment of type
2 diabetes. Herein, an integrated method consisting of enzyme kinetics, multi-spectroscopy …
2 diabetes. Herein, an integrated method consisting of enzyme kinetics, multi-spectroscopy …
Inhibition of α-glucosidase by trilobatin and its mechanism: kinetics, interaction mechanism and molecular docking
M He, Y Zhai, Y Zhang, S Xu, S Yu, Y Wei, H Xiao… - Food & Function, 2022 - pubs.rsc.org
… analysis in this study. The interaction mechanism between trilobatin and α-glucosidase in …
FT–IR as well as molecular docking analysis. This study probably expands new understanding …
FT–IR as well as molecular docking analysis. This study probably expands new understanding …
Inhibitory effect of phloretin on α-glucosidase: Kinetics, interaction mechanism and molecular docking
L Han, C Fang, R Zhu, Q Peng, D Li, M Wang - International Journal of …, 2017 - Elsevier
… In this study, multispectroscopic techniques and molecular docking analysis were used to …
on α-glucosidase. The results showed that phloretin reversibly inhibited α-glucosidase in a …
on α-glucosidase. The results showed that phloretin reversibly inhibited α-glucosidase in a …
α-Glucosidase inhibition by luteolin: Kinetics, interaction and molecular docking
J Yan, G Zhang, J Pan, Y Wang - International journal of biological …, 2014 - Elsevier
… (B) Cluster analysis of the AutoDock docking runs of luteolin with α-glucosidase. (For
interpretation of the references to color in this text, the reader is referred to the web version of the …
interpretation of the references to color in this text, the reader is referred to the web version of the …
Investigation the interaction between procyanidin dimer and α-glucosidase: Spectroscopic analyses and molecular docking simulation
… and α-glucosidase is poorly understood. In this study, spectroscopic analyses and computer
simulations were used to investigate the interactions between α-glucosidase and B-type …
simulations were used to investigate the interactions between α-glucosidase and B-type …
Inhibitory kinetics and mechanism of rifampicin on α-glucosidase: Insights from spectroscopic and molecular docking analyses
MZ Lin, WM Chai, YL Zheng, Q Huang… - International journal of …, 2019 - Elsevier
… on α-glucosidase were investigated by multispectroscopic methods along with molecular
docking technique. The results showed that rifampicin inhibited α-glucosidase activity …
docking technique. The results showed that rifampicin inhibited α-glucosidase activity …
Inhibitory mechanism of sinensetin on α-glucosidase and non-enzymatic glycation: Insights from spectroscopy and molecular docking analyses
D Liu, X Cao, Y Kong, T Mu, J Liu - International Journal of Biological …, 2021 - Elsevier
… α-glucosidase and non-enzymatic glycation was explored with multi-spectroscopic techniques
and molecular docking analysis … between sinensetin and α-glucosidase were studied. …
and molecular docking analysis … between sinensetin and α-glucosidase were studied. …
α-Glucosidase Inhibitors from Brickellia cavanillesii
S Escandón-Rivera, M González-Andrade… - Journal of natural …, 2012 - ACS Publications
… Docking analysis predicted … α-glucosidase, a molecular docking study was next performed
using the program AutoDock4. (31, 32) After geometric optimization, the ligands were docked …
using the program AutoDock4. (31, 32) After geometric optimization, the ligands were docked …
Phytochemical Analysis, α‐Glucosidase and Amylase Inhibitory, and Molecular Docking Studies on Persicaria hydropiper L. Leaves Essential Oils
… acarbose are the only three α-glucosidase inhibitors which are in … analyses the essential
oils against two important targets of the type-2 diabetes, α-glucosidase and α-amylase and dock …
oils against two important targets of the type-2 diabetes, α-glucosidase and α-amylase and dock …