Usefulness of a dopamine transporter PET ligand [18F] β-CFT in assessing disability in Parkinson's disease

JO Rinne, H Ruottinen, J Bergman… - Journal of Neurology …, 1999 - jnnp.bmj.com
… Our results show that striatal dopamine transporter uptake declines with increasing disability
in Parkinson's disease. Thus, [ 18 F]β-CFT is a useful ligand, not only in the diagnosis of …

Progression in Parkinson's disease: A positron emission tomography study with a dopamine transporter ligand [18F]CFT

E Nurmi, HM Ruottinen, V Kaasinen… - Annals of Neurology …, 2000 - Wiley Online Library
dopamine transporter function with PET during the progression of PD using [18F]CFT18,19
dopamine reuptake ligand. … [123I]FP-CIT SPECT shows a pronounced decline of striatal …

Reproducibility and Effect of Levodopa on Dopamine Transporter Function Measurements: A [18F]CFT PET Study

E Nurmi, J Bergman, O Eskola, O Solin… - Journal of Cerebral …, 2000 - journals.sagepub.com
… the usefulness of a dopamine transporter PET ligand, [ 18 F]CFT, in monitoring progression
… [ 18 F]CFT uptake and the normal variation of test–retest [ 18 F]CFT PET in healthy controls. …

Striatal Distribution of Dopamine Transporters and Dopamine D2 Receptors at Different Stages of Parkinson's Disease: A CFT and RAC PET Study

M Mishina, K Ishii, M Suzuki… - The Neuroradiology …, 2011 - journals.sagepub.com
… tion of dopaminergic system in the striatum of the patients with PD at different stages using
CFT, … Dopamine transporter imaging with [123I]FP-CIT SPECT: potential effects of drugs. Eur J …

Preparation of [18F]β‐CFTFP and [11C]β‐CFTFP, selective radioligands for visualisation of the dopamine transporter using positron emission tomography (PET)

EL Kämäräinen, T Kyllönen… - Journal of Labelled …, 2000 - Wiley Online Library
… that ß-CFT-FP should have a higher selectivity for DAT and should reach peak equilibrium
faster than the cocaine analogues mentioned above. We report the labelling of ß-CFT-FP with …

Radiosynthesis and Validation of 18F-FP-CMT, a Phenyltropane with Superior Properties for Imaging the Dopamine Transporter in Living Brain

P Cumming, S Maschauer, PJ Riss… - Journal of Cerebral …, 2014 - journals.sagepub.com
To date there is no validated, 18 F-labeled dopamine transporter (DAT) radiotracer with a …
phenyltropane 18 F-FP-CMT. Dynamic PET recordings were obtained for 18 F-FP-CMT in six …

Review of the use of dopamine transporter imaging agent 11C-β-CFT for diagnosing Parkinson disease

H Li, X Zhang, J Zhang - Int J Radiat Med Nucl Med, 2016 - ijrmnm.com
CFT binding to the striatal dopamine transporters in the Fischer 344 rats: a PET study[J]. Ann
Dopamine transporter imaging agent 11C鄄CFT and 18F鄄CFT and its clinical application …

[18F]CFT ([18F]WIN 35,428), a radioligand to study the dopamine transporter with PET: Characterization in human subjects

A Laakso, J Bergman, M Haaparanta, H Vilkman… - Synapse, 1998 - Wiley Online Library
dopaminergic neurons (substantia nigra) with [18F]CFT in some subjects. In conclusion, the
labeling of CFT … of extrastriatal dopamine transporters should become possible. Synapse …

Potential of [18F]β‐CFT‐FE (2β‐carbomethoxy‐3β‐(4‐fluorophenyl)‐8‐(2‐[18F]fluoroethyl)nortropane) as a dopamine transporter ligand: A PET study in the …

N Harada, H Ohba, D Fukumoto, T Kakiuchi… - Synapse, 2004 - Wiley Online Library
… -CFT-FP and [11C]-CFT-FP, selective radioligand for visualization of the dopamine transporter
… Severe depletion of cocaine recognition sites associated with the dopamine transporter in …

[(18) F] FDOPA and [(18) F] CFT are both sensitive PET markers to detect presynaptic dopaminergic hypofunction in early Parkinson's disease.

OJ Rinne, E Nurmi, HM Ruottinen… - Synapse (New York …, 2001 - europepmc.org
… )F]CFT), in detecting presynaptic dopaminergic hypofunction … different aspects of presynaptic
dopaminergic function, since [… [(18)F]CFT uptake is related to dopamine transporter function. …