Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs

D Charvin, R Medori, RA Hauser… - Nature Reviews Drug …, 2018 - nature.com
… In addition to dopaminergic neuropathology, there is … with dopamine system dysfunction
and/or dopaminergic neuronal … process affecting dopaminergic and non-dopaminergic systems (…

Factors associated with dopaminergic drug–related pathological gambling in Parkinson disease

V Voon, T Thomsen, JM Miyasaki… - Archives of …, 2007 - jamanetwork.com
… to adjuvant dopamine agonist therapy in Parkinson's disease and multiple system atrophy. …
AJ Hedonistic homeostatic dysregulation in patients with Parkinson's disease on dopamine

Contributions of dopaminergic drugs and disease severity to daytime sleepiness in Parkinson disease

PE O'Suilleabhain, RB Dewey Jr - Archives of neurology, 2002 - jamanetwork.com
… dosing and sedation, we reduce or change the offending drug. We compromise motor control
by reducing dopaminergic drugs only among the subset of patients with intolerance to all …

Molecular and clinical pathways to neuroprotection of dopaminergic drugs in Parkinson disease

AHV Schapira - Neurology, 2009 - AAN Enterprises
dopaminergic pathways to neuroprotection. The neuroprotective properties of dopaminergic
drugs … offer permanent relief of features related to dopamine deficiency. Also, the concept …

Mechanism of action of dopaminergic agents in Parkinson's disease

WC Koller, MG Rueda - Neurology, 1998 - AAN Enterprises
… How the actions of dopaminergic drugs produce side effects and how … Dopaminergic drugs,
levodopa and dopamine agonists, are highly effective in the treatment of Parkinson's disease

Factors influencing susceptibility to compulsive dopaminergic drug use in Parkinson disease

AH Evans, AD Lawrence, J Potts, S Appel, AJ Lees - Neurology, 2005 - AAN Enterprises
… to take dopaminergic drugs becomes pathologically … leads to compulsive dopaminergic drug
use 1,2 —the dopamine … brain dopamine systems mediating reward by dopaminergic drugs

Parkinson's disease, dopaminergic drugs and the plant world

P Kempster, A Ma - Frontiers in pharmacology, 2022 - frontiersin.org
dopamine deficiency in several ways—direct stimulation of dopamine receptors (levodopa,
dopamine receptor agonists), altering the balance between dopamine and acetylcholine in …

Acoustic voice analysis in patients with Parkinson's disease treated with dopaminergic drugs

J Gamboa, FJ Jiménez-Jiménez, A Nieto, J Montojo… - Journal of Voice, 1997 - Elsevier
To quantify several acoustic features of the voice in patients withParkinson's disease (PD),
41 patients and 28 age and sex-matched controls were studied. PD severity was assessed …

Non-dopaminergic treatments for motor control in Parkinson's disease

SH Fox - Drugs, 2013 - Springer
The pathological processes underlying Parkinson’s disease (PD) involve more than
dopamine cell loss within the midbrain. These non-dopaminergic neurotransmitters include …

Pharmacological treatment of Parkinson disease: a review

BS Connolly, AE Lang - Jama, 2014 - jamanetwork.com
… centrally to dopamine, replacing the neurotransmitter deficient in Parkinson disease. Outside
the blood-brain barrier, in the peripheral circulation, dopamine decarboxylase inhibitors (…