Increasing chemotherapy dose density and intensity: phase I trials in non-small cell lung cancer and non-Hodgkin's lymphoma

DW Blayney, BW McGuire, SE Cruickshank… - The …, 2005 - academic.oup.com
… No dose reduction was implemented in the event of hematologic toxicity in the previous …
dose reduction in the next cycle (or were reassigned to the next lower dosage cohort in the dose-…

Low-dose computed tomography screening reduces lung cancer mortality

M Ostrowski, T Marjański, W Rzyman - Advances in medical sciences, 2018 - Elsevier
reduction in patients who had undergone chest low-dose computed tomography (LDCT)
screening, as compared to patients screened with a conventional chest X-ray. Results of the …

… low lean body mass/body mass index are related to dose reduction and severe gastrointestinal toxicity induced by afatinib in patients with non-small cell lung cancer

O Arrieta, M De la Torre-Vallejo… - The …, 2015 - academic.oup.com
… This study on patients with non-small cell lung cancer treated with afatinib … dose-limiting
toxicity and severe gastrointestinal toxicity. Still more research needs to be done to explore dose

Adaptive radiotherapy in lung cancer: dosimetric benefits and clinical outcome

T Kataria, D Gupta, SS Bisht… - The British journal of …, 2014 - academic.oup.com
… Also, in the current study, replanning during treatment achieved significant reduction in
dose to normal tissue. Spoelstra et al 25 did not observe any significant change in …

Potential for reduced toxicity and dose escalation in the treatment of inoperable non–small-cell lung cancer: A comparison of intensity-modulated radiation therapy …

IS Grills, D Yan, AA Martinez, FA Vicini… - International Journal of …, 2003 - Elsevier
… techniques, there were relative reductions in the lung V 20 , mean lung dose, and lung NTCP
of … These reductions were even more profound when comparing IMRT to ENI, with the lung

Influence of dose adjustment on afatinib safety and efficacy in patients (pts) with advanced EGFR mutation-positive (EGFRm+) non-small cell lung cancer (NSCLC).

JCH Yang, MJ Ahn, NJ Dickgreber, B Halmos, V Hirsh… - 2015 - ascopubs.org
… the influence of afatinib dose reduction on adverse events (… III LUX-Lung 3 (LL3) trial, and
analyzed dose reduction data … 2 AEs on the initial 40 mg dose could dose reduce by 10 mg …

Adjuvant chemotherapy in resected stage II non-small cell lung cancer: evaluating the impact of dose intensity and time to treatment

K Ramsden, J Laskin, C Ho - Clinical Oncology, 2015 - Elsevier
… platinum dose and the total dose of … A dose reduction compared with the clinical trials was
adopted and agreed upon by the provincial Lung Tumor Group based on the dose reduction

[HTML][HTML] Low-dose gefitinib treatment for patients with advanced non-small cell lung cancer harboring sensitive epidermal growth factor receptor mutations

H Satoh, A Inoue, K Kobayashi, M Maemondo… - Journal of Thoracic …, 2011 - Elsevier
… the treatment with the standard dose, and a dose reduction of gefitinib by changing the
everyday schedule to every 2 days schedule was permitted when grade 2 toxicity was observed. …

Paclitaxel in advanced non-small cell lung cancer: an alternative high-dose weekly schedule

W Akerley III - Chest, 2000 - Elsevier
… When a dose reduction for neuropathy occurred, all future doses for that patient were limited
to 50% of original dose, … Other grade 3 and grade 4 toxicities also triggered dose omission. …

Early results of lung cancer screening and radiation dose assessment by low-dose CT at a community hospital

CD Jacobs, ME Jafari - Clinical lung cancer, 2017 - Elsevier
… used, and its effect on radiation dose reduction was not reflected in dose estimates. Readers
interested in estimation of CT examination organ doses that take into account both patient …