… enzymes and inhibited by deubiquitinating enzymes (DUBs). Genome-wide association studies
(GWASs) identified that polymorphisms in or in the vicinity of two human DUB … DUBs and …

… of proteases termed deubiquitinating enzymes (DUBs) or deubiquitinating peptidases.
Approximately 100 DUBs encoded in the human genome. These DUBs have been categorized …

… , deubiquitination, is reversible and involves the deconjugation of ubiquitin moieties from
protein substrates via multiple deubiquitinating enzymes (DUBs) [3]. Human DUBs belong to a …

… also be regulated by deubiquitinating enzymes (DUB), which cleave … deubiquitination in
the organism. The human genome encodes about 100 DUBs, which are usually divided into two …

… double-edged sword … deubiquitinating enzymes (DUBs)-mediated ubiquitin removal from
substrates is regulated by ROS. ROS-mediated oxidation of the catalytic cysteine (Cys) of DUBs…

… However, before they reach this protease assembly, their poly-Ub chain can be trimmed and
even completely removed by multiple deubiquitinating enzymes (DUBs). The DUB, UCH37, …

… enzymes including the LUBAC ligase complex, cIAP ligases, as well as DUBs such as the
OTU DUB … open, and how DUBs contribute to FADD-deubiquitination would be an important …

… referred to as a “double-edged” sword in the context of … the deubiquitinating enzymes (DUBs),
which are also called deubiquitinases, ubiquitin proteases and ubiquitin-hydrolases. DUBs …

… of deubiquitination for tricking host immune system wherein viral DUBs compete with host
DUBs … Interestingly, ubiquitination acts as double-edged sword wherein types of ubiquitination …

… , DUBs are usually formed as an active enzyme. However, in some cases, the catalytic activity
of DUBs … For example, there are indeed three DUBs directly associated with proteasome: …