Long non‑coding RNA GAS5 in human cancer

X Yang, Z Xie, X Lei, R Gan - Oncology letters, 2020 - spandidos-publications.com
… that GAS5 downregulation contributes to GC growth and affects patient prognosis (47–50).
GAS5 … The aforementioned findings suggest that GAS5 downregulation contributes to ESCC …

The RNA degradation pathway regulates the function of GAS5 a non-coding RNA in mammalian cells

H Tani, M Torimura, N Akimitsu - PloS one, 2013 - journals.plos.org
… the RNA degradation pathway can regulate this function of GAS5. We measured the
steady-state abundance and the decay rate of GAS5 in … RNA stability. We found that levels of the …

[HTML][HTML] Down-regulation of long non-coding RNA GAS5 is associated with the prognosis of hepatocellular carcinoma

ZQ Tu, RJ Li, JZ Mei, XH Li - International journal of clinical and …, 2014 - ncbi.nlm.nih.gov
GAS5 expression was an independent prognostic marker of overall HCC patient survival in
… time that GAS5 down regulated in a majority of HCC patients. Our results indicated that GAS5

Downregulation of GAS5 promotes bladder cancer cell proliferation, partly by regulating CDK6

Z Liu, W Wang, J Jiang, E Bao, D Xu, Y Zeng, L Tao… - PloS one, 2013 - journals.plos.org
… Here we performed a RNA pull-down assay to investigate the potential mechanism of
GAS5 in regulating cell growth. Our data revealed that GAS5 could combine with the cyclin-…

Growth arrest on inhibition of nonsense‐mediated decay is mediated by noncoding RNA GAS5

M Mourtada-Maarabouni… - BioMed research …, 2013 - Wiley Online Library
… whether down-regulation of GAS5 has any effect on the growth inhibitory effects of
gentamycin and G418. CEM-C7, Jurkat, and BJAB cells were transfected with GAS5 siRNA2 and …

[HTML][HTML] Long non-coding RNA GAS5 expression in patients with Down syndrome

M Salemi, G Marchese, A Cordella… - … Journal of Medical …, 2020 - ncbi.nlm.nih.gov
… If lncRNA GAS5 was down-expressed in the brain of DS subjects during embryonic … In
conclusion, we found that lncRNA GAS5 is down regulated in patients with DS compared to NS. …

[HTML][HTML] Downregulation of long non‑coding RNA GAS5 promotes cell proliferation, migration and invasion in esophageal squamous cell carcinoma

K Ke, Z Sun, Z Wang - Oncology letters, 2018 - spandidos-publications.com
… Although the regulatory mechanism of GAS5 in cellular migration and invasion has not … the
present study we hypothesize that lncRNA GAS5 may regulate cell migration and invasion in …

Downregulation of the long noncoding RNA GAS5-AS1 contributes to tumor metastasis in non-small cell lung cancer

Y Wu, H Lyu, H Liu, X Shi, Y Song, B Liu - Scientific reports, 2016 - nature.com
… the biological function of GAS5-AS1 in NSCLC, we first examined the impact of GAS5-AS1 …
Overexpression of GAS5-AS1 was achieved via transient transfection of pCDNA-GAS5-AS1 …

A critical role for the long non‐coding RNA GAS5 in proliferation and apoptosis in non‐small‐cell lung cancer

X Shi, M Sun, H Liu, Y Yao, R Kong… - Molecular …, 2015 - Wiley Online Library
GAS5 and its mechanism in NSCLC remains largely unknown. In the present study, we not
only found that GAS5 expression was significantly down-regulated … of GAS5 transcript, which …

Downregulation of long noncoding RNA Gas5 affects cell cycle and insulin secretion in mouse pancreatic β cells

F Jin, N Wang, Y Zhu, L You, L Wang, W De… - Cellular Physiology and …, 2018 - karger.com
… via glucose transporter regulation. LncRNA Gas5 was the key regulatory factor of mammalian
… In this study, we demonstrated that downregulation of lncRNA Gas5 expression resulted in …