Antimicrobial natural products: an update on future antibiotic drug candidates

M Saleem, M Nazir, MS Ali, H Hussain, YS Lee… - Natural product …, 2010 - pubs.rsc.org
pharmaceutical compendium, and the aim of this review is to explore and highlight the …
natural products that have potential to lead to more effective and less toxic antimicrobial drugs. …

Natural products in the process of finding new drug candidates

P Vuorela, M Leinonen, P Saikku… - Current medicinal …, 2004 - ingentaconnect.com
drug discovery involving the generation of truly novel molecular diversity from natural product
… solution to increase the productivity in drug discovery and development. Screening for new …

Screening of natural products for antimicrobial agents

L Silver, K Bostian - European Journal of Clinical Microbiology and …, 1990 - Springer
… A major part of the endeavor is in the historically productive area of natural product screening.
To make the best use of natural product resources for the discovery of novel antibiotics, a …

Opportunities for natural products in 21 st century antibiotic discovery

GD Wright - Natural product reports, 2017 - pubs.rsc.org
… in antibiotic drug discovery that threatens modern medicine. 21 st century natural product
positioned to fill the antibiotic discovery gap and bring new drug candidates to the clinic. …

New aspects of natural products in drug discovery

KS Lam - Trends in microbiology, 2007 - cell.com
… revolutionized the screening of natural products. Applying these technologies … natural
products and offers a unique opportunity to re-establish natural products as a major source for drug

Strategies for target identification of antimicrobial natural products

MA Farha, ED Brown - Natural product reports, 2016 - pubs.rsc.org
… for natural product discovery. Further, we discuss the more recent innovative approaches for
uncovering the target of new antibacterial natural products, … for antibacterial natural products

[HTML][HTML] Natural products in drug discovery: advances and opportunities

AG Atanasov, SB Zotchev, VM Dirsch… - Nature reviews Drug …, 2021 - nature.com
antimicrobial resistance. Here, we summarize recent technological developments that are
enabling natural product-based drug … for identifying improved drug candidates. For example, …

Natural products: an evolving role in future drug discovery

BB Mishra, VK Tiwari - European journal of medicinal chemistry, 2011 - Elsevier
… This review deals the clinical evaluation of 232 NP or their inspired drug candidates. … with
the advancement of antibiotics in the mid-twentieth century, drug formulations of fairly purified …

Something old, something new: revisiting natural products in antibiotic drug discovery

GD Wright - Canadian journal of microbiology, 2014 - cdnsciencepub.com
… The pharmaceutical industry has largely abandoned these … in identifying new natural product
antibiotics scaffolds. Advances … barriers to natural products. Coupled with new strategies in …

Natural products in drug discovery

AL Harvey - Drug discovery today, 2008 - Elsevier
… Another approach is to adapt the strategy long used to improve the activity of naturally
occurring antibiotics by applying … candidates in the current development pipeline that are of …