Identifying enriched drug fragments as possible candidates for metabolic engineering

S Sharma, K Karri, I Thapa, D Bastola, D Ghersi - BMC medical genomics, 2016 - Springer
… Therefore, medicinally important plants are often collected … limited knowledge about plant
secondary metabolism, its regulation… Obtaining a drug completely from a plant source is often a …

Evaluation of Plant Phenolic Metabolites as a Source of Alzheimer′ s Drug Leads

Y Hassaan, H Handoussa, AH El-Khatib… - BioMed Research …, 2014 - Wiley Online Library
… received considerable recent attention as alternative candidates for Alzheimer’s disease …
) as promising Alzheimer’s disease drug leads and using Camellia sinensis as reference …

Anti-diabetic potential of plant alkaloids: Revisiting current findings and future perspectives

H Rasouli, R Yarani, F Pociot… - Pharmacological …, 2020 - Elsevier
candidates for drug development. This review sets out to investigate the anti-diabetic potential
of plant … Traditionally, medicinal plants and their respected secondary metabolites such as …

Medicinal plants and bioactive natural compounds for cancer treatment: Important advances for drug discovery

F Majolo, LKOB Delwing, DJ Marmitt… - Phytochemistry …, 2019 - Elsevier
… derived from natural products as plants, marine organisms, … of the discovery of new
plant-derived metabolites for use in … indexed as potential anticancer drug candidates. Interestingly, …

Metabolomics and its potential in drug development

D Beyoğlu, JR Idle - Biochemical pharmacology, 2013 - Elsevier
… Many drug candidates fail during Phase II and III clinical trials at … plant metabolomics by Fiehn
and colleagues a decade ago [18]. … ion that was a candidate for a drug metabolite. Note the …

Plant-derived Antiviral Compounds as Potential COVID-19 Drug Candidates: In-silico Investigation in Search of SARS-CoV-2 Inhibitors

B Kolita, D Borah, P Hazarika, E Phukan, RR Borah - Trends in Sciences, 2023 - tis.wu.ac.th
… molecules from plant-derived antiviral compounds. In this study, 33 plantderived compounds
with … Inflammation and CYP3A4-mediated drug metabolism in advanced cancer: Impact and …

Toward the identification of natural antiviral drug candidates against merkel cell polyomavirus: computational drug design approaches

AH Asseri, MJ Alam, F Alzahrani, A Khames… - Pharmaceuticals, 2022 - mdpi.com
Plant secondary metabolites and … , plants have aided in the discovery or development of
over 60% of anticancer products, either directly or indirectly [18,19]. Previously, numerous plant

Pharmacokinetics and pharmacodynamics analysis of drug candidates

S Singh, DB Singh, B Gautam, A Singh, N Yadav - Bioinformatics, 2022 - Elsevier
… medicinal plants provides a new insight for novel drug designing… in the developmental state
of a drug candidate, and several … , metabolism, and excretion properties of a drug candidate (…

[PDF][PDF] Medicinal plants: Future source of new drugs

AK Shakya - International journal of herbal medicine, 2016 - researchgate.net
… to rediscover medicinal plants as a source of potential drug candidate. … of the medicinal plants
as a future source of herbal drugs. … Plantmetabolites are organic compounds which can be …

Specialized metabolites and valuable molecules in crop and medicinal plants: The evolution of their use and strategies for their production

V D'Amelia, T Docimo, C Crocoll, MM Rigano - Genes, 2021 - mdpi.com
… proteins that are needed as diagnostic reagents, vaccine candidates and even antiviral
drugs to fight against the pandemic caused by the coronavirus SARS-CoV-2 [106,107]. Different …