… -2 drugs and used a computational structure-activity relationship approach with emphasis
on 99 plant secondary metabolites from selected eight African medicinal plants with proven …

… proven its value for the development of novel drugs: natural products [11-13]. … candidate
compounds which have more “drug-like” properties (ie, in terms of absorption and metabolism) …

… of drugs that target bacterial virulence, a nonessential cellular process. Antivirulence drug
candidates … Xanthones, represented as the C 6 –C 1 –C 6 system, are secondary metabolites …

… metabolites from medicinal plants have been isolated. These are likely to provide lead
compounds for new drugs, … Parveen and coworkers when searching for potential drug candidates …

… such as plant-based drugs. The integration of secondary metabolites (SMs) produced by
plants … Several studies have highlighted evidence supporting the use of plant-based drugs in …

… and by differences in innate drug sensitivity among the … a variety of secondary plant metabolites
display antimalarial … present in a number of plants reputed in African traditional medicine …

… fungal bioactive metabolites from medicinal plants and their … from endophytic fungi stand a
chance as suitable candidates for … and high demand for nontoxic drugs have diversified in the …

… Natural drug-based chemotherapeutic have advanced at an unprecedented rate over the …
clinical implications in malignancies amongst other plant metabolites. It is widely debated how …

… metabolites on selected protein targets, in combination with the use of the candidate metabolites
… effective polyphenolic extracts or new drug candidates for pharmaceutical uses. Finally, …

… metabolites that organisms such as microbes and plants have evolved, largely for the purpose
of their own survival, has historically proved of immense benefit in drug … drug candidates …