… Here, we describe drugs/drug candidates that target proteases, such as malarial … Our
inhibitors are also described in this review article as examples of drugs that target proteases. © …

… will increasingly become valuable molecular probes for improving our understanding of
biological processes as well as commercially valuable drug candidates for treating diseases. …

… drug discovery with focus on the authors' drug discovery studies such as renin, HIV-protease,
and β-secretase inhibitors. … can form the scaffolding for drug candidates, namely substrate …

… ) of experimental drugs that inhibit enzymes called proteases, or more precisely a sub-class
of … inhibitors are promising therapeutic candidates for the treatment of inflammatory diseases. …

… of proteolytic events that lead … protease inhibitors as new drug candidates for leishmaniasis
therapeutic purposes. Moreover, proteases should be the excellent choice of targets for drug …

… inhibitors have been developed and are now widely used as research tools to study the
role of the ubiquitin–proteasome pathway in various cellular processes, and two inhibitors are …

… protease structure, function, and substrates, as well as the mechanism and the design of
inhibitors including the clinically approved drugs… drug candidates as HIV protease inhibitors and …

… of cysteine-, serine-, aspartic-, and metalloproteases that are considered lead molecules
and/or drug candidates for the treatment of leishmaniasis. Some of the compounds discussed in …

… Above all, there is a limited ligand specificity of existing protease-targeting drugs and drug
candidates. Many protease drug discovery efforts build on small molecules 1, 38, 39. However…

… In this review, we describe modern trends in the design of protease drugs as well as small …
These papers mostly focus on the classical ABPs in which protease inhibitors are labeled with …