Recent development of nanomedicine for the treatment of inflammatory diseases

M Higaki - Inflammation and Regeneration, 2009 - jstage.jst.go.jp
… Thus we need to develop a drug delivery system in particular nanocarriers, with enhanced
localization to the target site and sustained drug release. We have engineered nanoparticles …

Targeting strategies of oral nano-delivery systems for treating inflammatory bowel disease

W Liu, Z Dong, K Liu, Y Lu, W Wu, J Qi… - International Journal of …, 2021 - Elsevier
… considerations in terms of developing disease-directed drug delivery systems, then focuses
on mechanisms and strategies of current oral nano-drug delivery systems, including size-, …

Targeting pathophysiological changes using biomaterials-based drug delivery systems: A key to managing inflammatory bowel disease

S Mohajeri, S Moayedi, S Mohajeri… - Frontiers in …, 2022 - frontiersin.org
… of a drug, biomaterials-based drug delivery systems can be … design of biomaterials-based
drug delivery systems for efficient … using biomaterials-based drug delivery systems, which can …

Targeting inflammation to improve tumor drug delivery

V Gkretsi, LC Zacharia, T Stylianopoulos - Trends in cancer, 2017 - cell.com
… tumor drug delivery is imperative. We present here the main obstacles to drug delivery to
the … Furthermore, the use of anti-inflammatory agents is proposed as a promising alternative …

Oral colon-specific therapeutic approaches toward treatment of inflammatory bowel disease

B Xiao, D Merlin - Expert opinion on drug delivery, 2012 - Taylor & Francis
… Areas covered: This review addresses the main barriers for colon-specific drug delivery from
… Expert opinion: Oral colon-specific drug delivery represents a possible approach toward …

Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease

D Li, M Yang, H Xu, M Zhu, Y Zhang, C Tian… - Journal of Materials …, 2022 - pubs.rsc.org
… Colonic drug delivery relies on changes in gastrointestinal physiology, microbial changes,
and digestive enzymes in inflammatory bowel disease. Patients with IBD have significantly …

Macrophage-targeted delivery systems for nucleic acid therapy of inflammatory diseases

A Singh, M Talekar, A Raikar, M Amiji - Journal of controlled release, 2014 - Elsevier
delivery approach with reduced … delivery and absorption of drug through intestinal mucosa
while reducing systemic availability by promotion of first pass metabolism. The drug delivery

Oral delivery of antioxidant enzymes for effective treatment of inflammatory disease

Z Zeng, X He, C Li, S Lin, H Chen, L Liu, X Feng - Biomaterials, 2021 - Elsevier
… , we believe that the strategies we described here may provide a convenient and powerful
platform for the treatment of other inflammatory diseases. … Emerging frontiers in drug delivery

Natural anti-inflammatory compounds for the management and adjuvant therapy of inflammatory bowel disease and its drug delivery system

HJ Kim, C Neophytou - Archives of pharmacal Research, 2009 - Springer
… (IBD) including Ulcerative Colitis (UC) and Crohn Disease (CD) commencing immune-…
colonic drug delivery has gained increased importance not just for the treatment of local diseases

Nanoparticle-based oral drug delivery systems targeting the colon for treatment of ulcerative colitis

M Zhang, D Merlin - Inflammatory bowel diseases, 2018 - academic.oup.com
… -based drug delivery systems (DDS) may be promising tools for targeted delivery to the colon,
… This review highlights general considerations and limitations for oral drug delivery to the …