Engineering microneedle patches for vaccination and drug delivery to skin

MR Prausnitz - Annual review of chemical and biomolecular …, 2017 - annualreviews.org
Microneedle patches (MNPs) contain arrays of solid needles measuring hundreds of microns
in length that deliver drugs … , skin-insertion reliability, drug delivery efficiency, painlessness, …

Drug delivery using microneedle patches: not just for skin

JW Lee, MR Prausnitz - Expert opinion on drug delivery, 2018 - Taylor & Francis
… effectively blocks delivery of most molecules into the body [Citation1]. Microneedle patches
(… -scale pores that are large enough to enable drugs, including macromolecules, to enter the …

Microneedle patches as drug and vaccine delivery platform

J Li, M Zeng, H Shan, C Tong - Current medicinal chemistry, 2017 - ingentaconnect.com
… the recent advancements of microneedle patches in application for drugs and vaccine delivery.
… As a drug delivery tool, microneedle patches can deliver bioactive molecular of different …

Built‐in active microneedle patch with enhanced autonomous drug delivery

MA Lopez‐Ramirez, F Soto, C Wang… - Advanced …, 2020 - Wiley Online Library
… active MN delivery. Our methodology allowed the fabrication of a microneedle patch as well
for combinatorial delivery using spatially resolved active and passive microneedle zones, for …

[HTML][HTML] Application of microneedle patches for drug delivery; doorstep to novel therapies

FN Abrbekoh, L Salimi, S Saghati, H Amini… - Journal of tissue …, 2022 - ncbi.nlm.nih.gov
drug delivery systems (microneedle patches) in vitro and in vivo settings. In addition, we
discussed the influence of delivered drugs on … pathways through the intradermal delivery route. …

Application of microneedle patches for drug delivery; doorstep to novel therapies

F Nazary Abrbekoh, L Salimi… - Journal of Tissue …, 2022 - journals.sagepub.com
drug delivery systems (microneedle patches) in vitro and in vivo settings. In addition, we
discussed the influence of delivered drugs on … pathways through the intradermal delivery route. …

Microneedles in drug delivery: progress and challenges

M Avcil, A Çelik - Micromachines, 2021 - mdpi.com
… The advantages of microneedle patch technology have been extensively evaluated in the
… Like all new technologies, the microneedle patch application has great potential but is not …

Mass producible and biocompatible microneedle patch and functional verification of its usefulness for transdermal drug delivery

CY Jin, MH Han, SS Lee, YH Choi - Biomedical microdevices, 2009 - Springer
… are safety and delivery performance in addition to … methods for an inexpensive microneedle
patch made of biocompatible … microneedle patches as a transdermal drug delivery system. …

Development of dissolvable microneedle patches by CNC machining and micromolding for drug delivery

A Malek-Khatabi, ZF Rad, M Rad-Malekshahi… - Materials Letters, 2023 - Elsevier
microneedles using computer numerical control (CNC) machining and micromolding for
replicating dissolvable microneedles (DMNs) for drug delivery. … fabrication of microneedles. The …

Performance and characteristics evaluation of a sodium hyaluronate-based microneedle patch for a transcutaneous drug delivery system

Y Hiraishi, T Nakagawa, YS Quan, F Kamiyama… - International journal of …, 2013 - Elsevier
patch, the efficiency of drug delivery into the skin was determined by comparing (i) the residual
amount of ATRA on the MN patch … Using a mass balance, the amount of ATRA delivered