Poly (disulfide) s: from synthesis to drug delivery

R Zhang, T Nie, Y Fang, H Huang, J Wu - Biomacromolecules, 2021 - ACS Publications
… synthesis methods for poly(disulfide)s based on the … poly(disulfide)-based delivery systems
developed in recent years from a drug perspective, emphasizing both small-molecule drugs

A biodegradable polyphosphoester-functionalized poly (disulfide) nanocarrier for reduction-triggered intracellular drug delivery

P Ju, J Hu, F Li, Y Cao, L Li, D Shi, Y Hao… - Journal of Materials …, 2018 - pubs.rsc.org
delivery and efficient release of chemotherapeutic agents. In this work, given the unique
advantages of poly(disulfide)… copolymer poly(ethyl ethylene phosphate)-b-poly(disulfide)-b-poly(…

Disulfide-linked amphiphilic polymer-docetaxel conjugates assembled redox-sensitive micelles for efficient antitumor drug delivery

P Zhang, H Zhang, W He, D Zhao, A Song… - …, 2016 - ACS Publications
drug delivery system, we conjugated the anticancer drug DTX to our synthesized block polymers
mPEG-PBLG via disulfide … the redox-responsive drug delivery system for cancer therapy…

Facile synthesis of poly (disulfide) s through one-step oxidation polymerization for redox-responsive drug delivery

R Zhang, T Nie, L Wang, D He, Y Kang, C Zhang… - Biomaterials …, 2023 - pubs.rsc.org
poly(disulfide)s-based drug delivery systems. It has always been our hope to obtain bioactive
drug delivery … Hence, in this study, hydrophobic and biodegradable poly(disulfide)s (…

Hyperbranched vs. linear poly (disulfide) for intracellular drug delivery

S Bera, R Barman, S Ghosh - Polymer Chemistry, 2022 - pubs.rsc.org
… of drug delivery applications. To examine these issues, we have chosen two amphiphilic
poly(disulfide)… these two polymers in the context of their intracellular drug delivery applications. …

Synthesis strategies for disulfide bond-containing polymer-based drug delivery system for reduction-responsive controlled release

L Liu, P Liu - Frontiers of Materials Science, 2015 - Springer
… Over the past decades, numerous efforts have been devoted for developing safe and effective
drug delivery systems (DDSs) for selective delivery of the toxic anti-cancer drugs to tumors…

Design of controlled drug delivery system based on disulfide cleavage trigger

D Yang, W Chen, J Hu - The Journal of Physical Chemistry B, 2014 - ACS Publications
disulfide bond has drawn increasing attention for the application on controlled drug delivery
… that the concentration of glutathione (GSH), a disulfide-bond-breaking agent, in the tumor …

Intracellular delivery of functional proteins and native drugs by cell-penetrating poly (disulfide) s

J Fu, C Yu, L Li, SQ Yao - Journal of the American Chemical …, 2015 - ACS Publications
The efficient delivery of bioactive compounds into cells is a major challenge in drug discovery.
We report herein the development of novel methods for intracellular delivery of functional …

Disulfide cross‐linked polyurethane micelles as a reduction‐triggered drug delivery system for cancer therapy

S Yu, J Ding, C He, Y Cao, W Xu… - Advanced healthcare …, 2014 - Wiley Online Library
… We present a novel and facile strategy to develop disulfide core cross-linked micelles
based on polyurethanes for intracellular site-specific drug delivery. The disulfide core cross-linked …

Redox-and pH-sensitive polymeric micelles based on poly (β-amino ester)-grafted disulfide methylene oxide poly (ethylene glycol) for anticancer drug delivery

QN Bui, Y Li, MS Jang, DP Huynh, JH Lee… - Macromolecules, 2015 - ACS Publications
In this report, a redox- and pH-sensitive poly(β-amino ester)-grafted disulfide methylene oxide
poly(ethylene glycol) (PAE-g-DSMPEG) was synthesized, and it showed not only a sharp …