… early in the process of drug development, ideally before new drugs are marketed. This …
approval of a new drug into subsequent recommendations for combination treatment regimens. It …

… in the treatment of tuberculosis, the global pipeline of new compounds that are in clinical
development, and draw attention to the challenges in drug research and development. Issues …

… in clinical phases 2 or 3 for treating tuberculosis. In addition, analogues of known TB drugs
(PA-824, … Small molecules in clinical trials or preclinical development to treat tuberculosis are …

… in all stages of TB drug development, starting from hit discovery and target validation to late-…
of drugs in TB granulomas and how they relate to clinically observed treatment failures and …

… TB treatment duration. This review summarizes the current TB drug development pipeline
and proposes strategies for generating improved hits and leads in the discovery phase that …

… the development of new drugs. In this review, we highlight the reasons that make TB drug
discovery and development … directions and alternative approaches to new therapeutics for TB. …

… , the anti-TB drug pipeline is in … on treatment strategies and challenges. We review new
technological advances in mycobacteriology, their impact on TB drug discovery and development…

… challenges of drug development are augmented in TB by the … -drug regimens, the relative
lack of TB drug development for … there is a robust enough pipeline of drugs in development to …

… The moxifloxacin clinical development program is being coordinated through a joint partnership
between Bayer and The Global Alliance for TB Drug Development (TB Alliance). Clinical …

… moieties which are at present in the pipeline has been summarized in this review. … history
of tuberculosis and the drug development against TB as well as the recent drug development. …