… and functions of condensates may enable a novel approach to drug discovery. After briefly
… formation of biomolecular condensates, we outline the diverse roles that condensates play …

… field of condensates likely to influence drug discovery, particularly … how condensates may
aid modulation of difficult-to-drug … into a drug discovery era that integrates the evolving fields of …

… There is a long list of open questions for drug hunters to consider. What happens if a
prioritized target clusters in transient biomolecular condensates? Does the diffusion of drugs into …

… condensate in ways that could be used for drug discovery in … biomolecular condensates
are unconventional drug targets, out of the reach of conventional structure-based drug discovery …

… a focus on understanding condensate functions. Studies have … and cellular functions of
biomolecular condensates from the recent … of the widespread roles of condensates in cell biology. …

… that contribute to biomolecular condensate formation and … in specific condensates and argue
that deeper insights into condensate … Condensates formed with different biomolecules have …

… Fellow at the University of Cambridge and presently directs computational research at
Transition Bio, a company focused on drug discovery against biomolecular condensate targets. …

… ) on the therapeutic index of these drugs. As nucleic acids are key components of biomolecular
condensates, we hypothesized that these drugs were likely to partition into condensates …

… viral biomolecular condensates and extrapolate connections between viral replication cycle
… biomolecular condensates. Finally, we will discuss how condensate-targeted drug discovery …

… Condensates are membrane-less bodies, often formed by … New insights from condensate
studies portend a profound … Here we summarize key features of biomolecular condensates, …