Publisher Summary This chapter focuses on the molecular mechanism of action (MMoA) in
drug discovery. MMoA of a medicine is the connection of the molecular interactions between …

… mechanism-of-action studies have important roles in small-molecule probe and drug
discovery. … to discover new biologically active small molecules. Such studies allow small-molecule …

… are promising glycomics projects in drug discovery. … The knowledge about these already
clarified mechanisms … the drug discovery and development of fucanomics and galactanomics. …

… many beneficial drugs in use for which the target and mechanism of action remain unknown…
and mechanism of action should be elucidated very early in the drug discovery process due …

… : Mechanisms of Action, Resistance, and New Directions in Drug Discovery offers detailed
… If this is the case, and we can help to expand efforts toward antimalarial drug discovery and …

… in drug discovery, especially structure-based drug discovery, has been described in different
reviews [32,60,61,62,63]. In this review, we elucidate mechanisms of action … drug discovery. …

… drug discovery. However, owing to the complexity of compounds and their related multiple
targets of TCM, it remains difficult to dissect the mechanisms of action … mechanisms of action of …

… in drug MOA elucidation in the entire drug discovery field, in … assessment of MOA in TB drug
discovery with an emphasis on … to deliver drug candidates in TB drug discovery and expand …

… (21, 22) This Perspective illustrates the integral role that molecular modeling played in our
recent drug discovery project and emphasizes its synergetic use with modern experimental …

… to determine specific mechanisms of toxicity for many toxicants. A means to address this
deficiency lies in utilization of a vast repertoire of tools developed by the drug discovery industry …