Machine learning: A new approach for dose individualization

QY Li, BH Tang, YE Wu, BF Yao… - Clinical …, 2024 - Wiley Online Library
… the prediction model using at least one ML algorithm, (2) were focused on dose
individualization (eg, for the prediction of drug dose or exposure related parameters or assisting …

Machine Learning Methods for Precision Dosing in Anticancer Drug Therapy: A Scoping Review

O Teplytska, M Ernst, LM Koltermann… - Clinical …, 2024 - Springer
… Overall, this review emphasises the clinical relevance of Machine Learning methods for
anticancer drug dose optimisation, as many algorithms have shown promising results enabling …

Artificial intelligence and machine learning approaches to facilitate therapeutic drug management and model-informed precision dosing

EA Poweleit, AA Vinks, T Mizuno - Therapeutic drug monitoring, 2023 - journals.lww.com
drug monitoring (TDM) and model-informed precision dosing (… intelligence (AI) and machine
learning (ML) approaches for … However, AI and ML applications for precision dosing have …

Machine Learning as a Novel Method to Support Therapeutic Drug Management and Precision Dosing.

T Gelder, AA Vinks - Clinical Pharmacology & Therapeutics, 2021 - search.ebscohost.com
… of more machine learning algorithms to support therapeutic drug management and model-
informed precision dosing for other categories of drugs? Will machine learning take over from …

Applications of machine learning in decision analysis for dose management for dofetilide

AE Levy, M Biswas, R Weber, K Tarakji, M Chung… - PLoS …, 2019 - journals.plos.org
… period for drug initiation[10]. There is a recommended algorithm for making dose adjustments
… the patterns of dofetilide dose adjustment and the role of machine learning to develop …

Improvement of adequate digoxin dosage: an application of machine learning approach

YH Hu, CT Tai, CF Tsai… - Journal of healthcare …, 2018 - Wiley Online Library
dosing. To the best of our knowledge, this study first adopts machine learning techniques
to construct digoxin dosage … only 8 drug types for DDIs; in this study, a total of 26 drugs with …

Machine learning-based quantitative prediction of drug exposure in drug-drug interactions using drug label information

HY Jang, J Song, JH Kim, H Lee, IW Kim, B Moon… - NPJ Digital …, 2022 - nature.com
… to perform drug interaction tests for all possible drug pairs. Our machine learning approach
to … to different drug doses, results using the standard dose were selected. However, if several …

Using machine learning to model dose–response relationships

A Linden, PR Yarnold… - Journal of Evaluation in …, 2016 - Wiley Online Library
… to evaluate dose–response relationships must be able to account for autocorrelation when
individuals are subjected to multiple doses of the exposure (eg increasing doses of a drug). …

A new algorithm optimized for initial dose settings of vancomycin using machine learning

S Imai, Y Takekuma, T Miyai… - Biological and …, 2020 - jstage.jst.go.jp
… setting, although it is possible that ML can help achieve accurate drug dose settings. … of ML
for drug dose setting. Our aim was to construct an optimal algorithm for initial dose settings of …

A data-driven predictive approach for drug delivery using machine learning techniques

YY Li, SC Lenaghan, M Zhang - PLoS One, 2012 - journals.plos.org
… for a drug resistant strain to … dose, thus minimizing excessive drug, machine learning
techniques were used to develop a framework for analyzing the trade-off between the drug dosage