Impact of nutritional status on the pharmacokinetics of erlotinib in rats
A Pérez‐Pitarch, A Nacher, V Merino… - … & Drug Disposition, 2015 - Wiley Online Library
… and serum albumin levels. … humans and WN rats, since the co-solvents used in the solution
formulation may have prevented pre-systemic drug loss due to the low solubility of erlotinib. …
formulation may have prevented pre-systemic drug loss due to the low solubility of erlotinib. …
Synthesis, characterization and in vitro anti-tumoral evaluation of Erlotinib-PCEC nanoparticles
… CL block copolymers which used in encapsulation of bovine serum albumin(BSA), taxol and
… with different concentration of erlotinib solution and drug loaded nanoparticles are shown in …
… with different concentration of erlotinib solution and drug loaded nanoparticles are shown in …
Tumor vasculature normalization by orally fed erlotinib to modulate the tumor microenvironment for enhanced cancer nanomedicine and immunotherapy
… By using human serum albumin (HSA)-bound paclitaxel (PTX) as the model nanomedicine
drug, it is found that erlotinib treatment could greatly enhance the efficacy of nanoparticle-…
drug, it is found that erlotinib treatment could greatly enhance the efficacy of nanoparticle-…
[PDF][PDF] Erlotinib enhances metabolism of phenytoin: A case report
MC Su, CC Wang, KT Huang, CH Lie… - … Journal of Medicine …, 2010 - academicjournals.org
… the serum phenytoin level before the introduction of erlotinib. … low serum albumin level in
this patient. Accordingly, it is highly possible that the introduction of erlotinib lowered the serum …
this patient. Accordingly, it is highly possible that the introduction of erlotinib lowered the serum …
EGF receptor inhibitor erlotinib as a potential pharmacological prophylaxis for posterior capsule opacification
… Unspecific binding was blocked by bovine serum albumin at 3 mg/… The human plasma
concentration considered to be safe (… The co-medication, mode of application and the application …
concentration considered to be safe (… The co-medication, mode of application and the application …
Plasma and Pleural Fluid Pharmacokinetics of Erlotinib and its Active Metabolite OSI-420 in Patients With Non–Small-Cell Lung Cancer With Pleural Effusion
K Masago, Y Togashi, M Fukudo, T Terada, K Irisa… - Clinical Lung Cancer, 2011 - Elsevier
… The area under the drug concentration-time curve of pleural fluid for erlotinib was 28,406
ng-… using blank human plasma and MPE samples from different donors. Blood samples were …
ng-… using blank human plasma and MPE samples from different donors. Blood samples were …
Preparation of radiolabeled erlotinib analogues and analysis of the effect of linkers
A Jain, A Kumar, R Vasumathy, S Subramanian… - Bioorganic & Medicinal …, 2022 - Elsevier
… high in vitro stability in human serum up to 48 h. They … drug itinerary for tyrosine kinase
receptor targeted therapy of patients.9, 10, 11 Here in this report analogues of the TKI erlotinib …
receptor targeted therapy of patients.9, 10, 11 Here in this report analogues of the TKI erlotinib …
Erlotinib hydrochloride novel drug delivery systems: a mini review unravelling the role of micro-and nanocarriers
C Taiwade, A Fulfager, H Bhargave, G Soni… - Drug Delivery …, 2021 - ingentaconnect.com
… Shen and Li developed erlotinib loaded hyaluronic acid and human serum albumin co-modified
NPs (ERT-HSA-HA NPs) by applying the precipitation method [65]. The mean particle …
NPs (ERT-HSA-HA NPs) by applying the precipitation method [65]. The mean particle …
[HTML][HTML] A multifunctional nanotheranostic agent potentiates erlotinib to EGFR wild-type non-small cell lung cancer
… NC membrane was blocked with 5% bovine serum albumin (BSA) in triethanolamine … To
dissect the details regarding the vessel normalization dynamics after drug administration, we …
dissect the details regarding the vessel normalization dynamics after drug administration, we …
Population pharmacokinetics of erlotinib in J apanese patients with advanced non‐small cell lung cancer
Y Emoto‐Yamamoto, S Iida… - Journal of Clinical …, 2015 - Wiley Online Library
… Erlotinib is now used as an antineoplastic drug in the treatment of NSCLC in over 90 countries.
In Japan, erlotinib … of erlotinib is considered to be bound to human serum albumin and …
In Japan, erlotinib … of erlotinib is considered to be bound to human serum albumin and …