Mesoporous silica nanoparticles as delivery carriers: An overview of drug loading techniques

KB Seljak, P Kocbek, M Gašperlin - Journal of Drug Delivery Science and …, 2020 - Elsevier
… high drug loading of MSNs. In this review, we describe different drug loading procedures …
While MSNs are usually presented as drug delivery system enabling high drug loading, this …

Mesoporous silica nanoparticles: synthesis, classification, drug loading, pharmacokinetics, biocompatibility, and application in drug delivery

Z Li, Y Zhang, N Feng - Expert opinion on drug delivery, 2019 - Taylor & Francis
… Before drug loading, the characteristics of MSNs should be taken into consideration. In … their
biocompatibility, control the release of drugs loaded into the MSNs or enhance the uptake of …

Impact of the strategy adopted for drug loading in nonporous silica nanoparticles on the drug release and cytotoxic activity

B Riva, M Bellini, E Corvi, P Verderio, E Rozek… - Journal of colloid and …, 2018 - Elsevier
… performed on drug loading and drug release, silica matrix … adopted for drug incorporation
and nanoparticle behavior in a … the prodrug nanoparticles on the kinetics and efficacy of drug

Development of high‐drugloading nanoparticles

Y Liu, G Yang, S Jin, L Xu, CX Zhao - ChemPlusChem, 2020 - Wiley Online Library
… on developing nanoparticles with high drug loading (>10 wt%… , including post-loading,
co-loading, and pre-loading. Based … -loaded silica nanoparticles with drug loading of 35–47 %.57 …

A comprehensive study of drug loading in hollow mesoporous silica nanoparticles: impacting factors and loading efficiency

L Guo, J Ping, J Qin, M Yang, X Wu, M You, F You… - Nanomaterials, 2021 - mdpi.com
… reported HMSNs and drugs. To this end, we herein made a comprehensive study on drug
loading in HMSNs from the viewpoint of impacting factors and loading efficiency. Specifically, …

The engineering of porous silica and hollow silica nanoparticles to enhance drug-loading capacity

NT Nguyen-Thi, LP Pham Tran, NTT Le, MT Cao… - Processes, 2019 - mdpi.com
… As a promising candidate for expanding the capacity of drug loading in silica nanoplatforms,
hollow mesoporous silica nanoparticles (HMSNs) are gaining increasing attention. In this …

Functionalized mesoporous silica nanoparticles as delivery systems for doxorubicin: drug loading and release

CM Day, MJ Sweetman, Y Song, SE Plush, S Garg - Applied Sciences, 2021 - mdpi.com
… described the loading capacity and in vitro release kinetics of mesoporous silica nanoparticles
(MSNs), functionalized with Poly-L-Histidine and Tamoxifen. The model drug Doxorubicin …

Mesoporous silica nanoparticles: Synthesis, functionalization, drug loading and release-A review

BB Galabova - Tropical Journal of Pharmaceutical Research, 2021 - ajol.info
… the synthesis of several types of mesoporous silica nanoparticles and their uses as drug
delivery nanocarriers is presented in this study. Mesoporous silica nanoparticles (MSNs) have a …

Mesoporous silica nanoparticles: selective surface functionalization for optimal relaxometric and drug loading performances

M Bouchoucha, R C.‐Gaudreault… - Advanced Functional …, 2014 - Wiley Online Library
drug carriers, as demonstrated with a model of daunorubicin submitted to physiological
conditions. The selective nanoparticle … stability silica-based vectors with high drug loading

Spherical mesoporous silica nanoparticles for loading and release of the poorly water-soluble drug telmisartan

Y Zhang, Z Zhi, T Jiang, J Zhang, Z Wang… - Journal of Controlled …, 2010 - Elsevier
… to develop mesoporous silica nanoparticles (MSNs) loaded with a poorly water-soluble drug,
… were the two main factors limiting the maximum drug load capacity. MSNs allow a very high …