Non-clinical models to determine drug passage into human breast milk
… breastfeeding when their mothers are prescribed medication … governing drug transfer rates
into human breast milk and the … drug properties may provide a rough estimation of blood/milk …
into human breast milk and the … drug properties may provide a rough estimation of blood/milk …
Molecular descriptors that influence the amount of drugs transfer into human breast milk
S Agatonovic-Kustrin, LH Ling, SY Tham… - … of Pharmaceutical and …, 2002 - Elsevier
… Most drugs are excreted into breast milk to some extent and … of drug that might be present
in milk from the drug structure … to select descriptors that effect drug passage into breast milk. …
in milk from the drug structure … to select descriptors that effect drug passage into breast milk. …
Drug excretion in breast milk
H Vorherr - Postgraduate Medicine, 1974 - Taylor & Francis
… pores may permit passage of watersoluble drug molecules with … , drugs contained in breast
milk may cause idiosyncrasy. For instance, hemolytic anemia induced by drugs in breast milk …
milk may cause idiosyncrasy. For instance, hemolytic anemia induced by drugs in breast milk …
Drugs and chemical contaminants in human breast milk
A Anadón, MR Martínez-Larrañaga, I Ares… - Reproductive and …, 2017 - Elsevier
… the extent of drug excretion in human breast milk is not available and for many drugs data
from … Because the blood–brain barrier (BBB) is not fully developed in neonates, drug passage …
from … Because the blood–brain barrier (BBB) is not fully developed in neonates, drug passage …
Principles of drug transfer into breast milk and drug disposition in the nursing infant
RL Breitzka, TL Sandritter… - Journal of human …, 1997 - journals.sagepub.com
… to drug passage into breast milk. Pharmacokinetics is the study of drug movement throughout
the body… More specifically it is the study of the relationship between drug dosage and drug …
the body… More specifically it is the study of the relationship between drug dosage and drug …
[HTML][HTML] An in vitro human mammary epithelial cell permeability assay to assess drug secretion into breast milk
… breastfeeding infants and did not take any medications. The process of human breast milk
… IRB) and all donors signed the informed consent before donating the breastmilk. Expressed …
… IRB) and all donors signed the informed consent before donating the breastmilk. Expressed …
[HTML][HTML] Drug distribution in human milk
KF Ilett, JH Kristensen… - Australian …, 1997 - australianprescriber.tg.org.au
… of drugs and environmental chemicals into human milk continues … aware of the possible risks
to the breast-fed infant. There is … passage of low molecular weight heparin into human milk …
to the breast-fed infant. There is … passage of low molecular weight heparin into human milk …
Passage of paracetamol into breast milk and its subsequent metabolism by the neonate.
LJ Notarianni, HG Oldham… - British journal of clinical …, 1987 - Wiley Online Library
… of paracetamol received in milk is dependent on milk flow and is a variable that should be
taken into account in the design and interpretation of studies of drug passage into breast milk. …
taken into account in the design and interpretation of studies of drug passage into breast milk. …
Modeling drug passage into human milk
PO Anderson, JB Sauberan - Clinical Pharmacology & …, 2016 - Wiley Online Library
… drug passage into breastmilk is the administration of a drug to a … the drug therapeutically.
After administration, several timed … milk with a breast pump can overestimate the volume of milk …
After administration, several timed … milk with a breast pump can overestimate the volume of milk …
Biological barriers, and the influence of protein binding on the passage of drugs across them
K Wanat - Molecular biology reports, 2020 - Springer
… also bind with the breast milk proteins themselves [112]. The composition of the protein …
drug binding is typically weaker in breast milk than in plasma [111]. Drug transfer into breast milk …
drug binding is typically weaker in breast milk than in plasma [111]. Drug transfer into breast milk …
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